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Table 4 Demographic and genetic factors associated with daily stable warfarin dose by multiple linear regression

From: Impact of VKORC1, CYP4F2 and NQO1 gene variants on warfarin dose requirement in Han Chinese patients with catheter ablation for atrial fibrillation

Factors Standardized coefficient P-value
Age −0.077 < 0.001
Gender −0.14 < 0.001
Body Surface Area −0.05 < 0.001
SNP of VKORC1 0.150047 < 0.001
SNP of CYP4F2 −0.0299 < 0.001
SNP of NQO1 0.087033 0.12
  1. Variables (age, body surface area, gender and variation of SNPs) associated with warfarin dose were analyzed by Pearson’s correlation coefficient and the χ2-test. Variables with P ≤ 0.1, and not strongly correlated with other factors, were analyzed by multiple linear regression analysis to find their joint association with warfarin dose. P < 0.05 was considered to be statistically significant