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Table 4 Demographic and genetic factors associated with daily stable warfarin dose by multiple linear regression

From: Impact of VKORC1, CYP4F2 and NQO1 gene variants on warfarin dose requirement in Han Chinese patients with catheter ablation for atrial fibrillation

Factors

Standardized coefficient

P-value

Age

−0.077

< 0.001

Gender

−0.14

< 0.001

Body Surface Area

−0.05

< 0.001

SNP of VKORC1

0.150047

< 0.001

SNP of CYP4F2

−0.0299

< 0.001

SNP of NQO1

0.087033

0.12

  1. Variables (age, body surface area, gender and variation of SNPs) associated with warfarin dose were analyzed by Pearson’s correlation coefficient and the χ2-test. Variables with P ≤ 0.1, and not strongly correlated with other factors, were analyzed by multiple linear regression analysis to find their joint association with warfarin dose. P < 0.05 was considered to be statistically significant
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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