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Table 3 The allelic frequencies and genotype distributions in Sichuan Han Chinese patients with catheter ablation of atrial fibrillation

From: Impact of VKORC1, CYP4F2 and NQO1 gene variants on warfarin dose requirement in Han Chinese patients with catheter ablation for atrial fibrillation

Gene

SNP

Genotype

Patient Number (%)

Mean stable warfarin dose±SD (mg/day)

Allele

Frequency Number (%)

NQO1

rs1800566

CC

90(78)

2.33 ± 0.1

C

202(87)

  

CT

22(19)

2.46 ± 0.24

T

30(13)

  

TT

4(3)

3.01 ± 0.27

  

VKORC1

rs9923231

GG

1(0.4)

7.19

G

45(10)

  

AG

43(19)

3.03 ± 0.28

A

399(90)

  

AA

178(80)

2.52 ± 0.07

  

CYP4F2 V433 M

rs2108622

CC

155(70)

2.41 ± 0.08

C

356(80.5)

  

CT

46(20)

3.38 ± 0.22

T

86(19.5)

  

TT

20(9)

2.79 ± 0.19

  
  1. SNP single nucleotide polymorphism