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Table 3 Frequency and incidence of events in the population with co-treatment with antiplatelets (n = 3573)

From: Safety of cilostazol in peripheral artery disease: a cohort from a primary healthcare electronic database

  

Risk at 5 years

   

Outcomes

N

(%)

CI95%

HR

CI95%

p valuea

Gastrointestinal haemorrhage

 Cilostazol

15

0.8

0.4–1.3

0.67

0.3–1.3

0.232

 Pentoxifylline

22

1.2

0.7–1.8

   

Cerebral haemorrhage

 Cilostazol

14

0.8

0.4–1.2

1.23

0.6–2.7

0.604

 Pentoxifylline

13

0.7

0.3–1.1

   

Other haemorrhages

 Cilostazol

55

3.1

2.3–3.9

0.65

0.5–0.9

0.014

 Pentoxifylline

85

4.8

3.8–5.8

   

Any haemorrhage

 Cilostazol

69

3.8

3.0–4.7

0.72

0.5–1.0

0.040

 Pentoxifylline

98

5.5

4.5–6.6

   

CAD

 Cilostazol

224

12.5

10.9–14.0

0.93

0.8–1.1

0.427

 Pentoxifylline

237

13.3

11.8–14.9

   

Stroke

 Cilostazol

103

5.7

4.7–6.8

0.83

0.6–1.1

0.180

 Pentoxifylline

121

6.8

5.6–8.0

   

AF

 Cilostazol

122

6.8

5.6–8.0

1.0

0.8–1.3

0.999

 Pentoxifylline

120

6.8

5.6–7.9

   

Other arrhythmias

 Cilostazol

61

3.4

2.6–4.2

1.42

1.0–2.1

0.082

 Pentoxifylline

42

2.4

1.7–3.1

   
  1. CI 95% Confidence Interval with 95%, HR hazard ratio, CAD coronary artery disease, AF atrial fibrillation
  2. ap-value computed using univariate Cox regression with robust standard errors by clusters (pairs)
  3. Significant p-values in boldface