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Table 5 Predictors of increasing costs

From: Cost-of-illness studies in heart failure: a systematic review 2004–2016

Reference

Predictors of increasing costs (x times higher costs)

Stafylas, 2016

• NYHA stage

• Kidney dysfunction

Lee, 2016 [31]

• Age > = 65 (1.6)

• Number of hospitalizations (9.7 for one hospitalization)

Bogner, 2010 [24]

• Diabetes mellitus (0.4)

Dunlay, 2011 [34]

• Diabetes mellitus (0.25)

• Ejection fraction > = 50 (0.24)

Liao, 2006 [25]

• NYHA stage (NYHA 4–0.77, NYHA 3–0.12)

• Kidney dysfunction (creatinine > = 1.4 mg/dl – 0.48)

• Coronary artery disease (0.32)

• COPD (0.38)

• Hypertension (0.27)

Liao, 2007 [23]

• NYHA stage (NYHA 3/4–0.41)

• Coronary artery disease (0.66)

• Kidney dysfunction (0.13)

• COPD (0.44)

Delgado, 2013

• NYHA stage (NYHA 3/4: 0.6–0.8 times higher costs than NYHA 2)