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Table 2 Cause- Specific Hazard Ratios for Microsize MI and Typical MI according to Baseline Brain Natriuretic Peptide (NT-proBNP) Tertiles

From: N-terminal pro-B-type natriuretic peptide and microsize myocardial infarction risk in the reasons for geographic and racial differences in stroke study

  Events Microsize MI Events Typical MI P for equality a
Model 1
< 42.50(Ref) 16 1 73 1 0.03
42.5–115.5 46 3.11 (1.70–5.69) 97 1.41 (0.98–2.04)
≥ 115.50 77 7.06 (3.96–12.57) 145 2.86 (2.02–4.05)
Model 2
< 42.50(Ref) 16 1 73 1 0.03
42.5–115.5 46 3.18 (1.62–6.26) 97 1.26 (0.80–1.99)
≥ 115.5 77 6.83 (3.52–13.25) 145 2.66 (1.63–4.33)
  1. Model 1 = BNP alone
  2. Model 2 = Model 1 + Demographics (age, race, sex, household income, education, geographic region of residence), additional Framingham risk factors (current smoking status, systolic blood pressure, diabetes, HDL and total cholesterol) and other CVD risk factors and covariates (body mass index, log-transformed hsCRP, log-transformed ACR and medication use
  3. All models tested for interactions of NT-proBNP with age, race and gender
  4. Bold p < 0.05
  5. a Cause specific model using Lunn and McNeil approach for competing risk analyses