Skip to main content

Table 1 Baseline Characteristics of Study Participants in the Cohort Random Sample by Tertiles of NT-proBNP

From: N-terminal pro-B-type natriuretic peptide and microsize myocardial infarction risk in the reasons for geographic and racial differences in stroke study

  Brain Natriuretic Peptide (N-terminal pro BNP), tertiles of pg/mL
Characteristics* < 42.5 42.5–115.5 ≥115.5 p-value †
Total participants, n 278 280 289  
Male, n (%) 168 (60.4) 119 (42.5) 101 (35.0) < 0.001
African American, n (%) 168 (56.8) 129 (46.1) 142 (49.1) 0.03
Age in years, mean (SD) 59.7 ± 9.5 65.9 ± 11.2 74.5 ± 10.9 < 0.001
Less than High School education, n (%) 28 (10.1) 38 (13.6) 61 (21.1) 0.001
Annual Income, n (%)     0.001
  < $20,000 38 (13.7) 46 (16.4) 71(24.6)
 ≥$20,000 208 (74.8) 193 (68.9) 157 (54.3)
 Declined to report 32 (11.5) 41 (14.6) 61 (21.1)
Current smoking, n (%) 46 (16.6) 41 (14.7) 33 (11.5) 0.21
Systolic blood pressure, mmHg, mean (SD) 125 ± 14.8 127 ± 17.4 130.8 ± 18.0 < 0.001
High density lipoprotein, mg/L, mean (SD) 50.0 ± 14.7 53.1 ± 17.0 54.0 ± 18.7 0.005
Total cholesterol, mg/L, mean (SD) 196 ± 41 192 ± 37 186 ± 37 < 0.001
Diabetes, n (%) 52 (19.1) 49 (17.8) 59 (20.6) 0.67
Body mass index, kg/m2, mean (SD) 29.8 ± 5.7 29.1 ± 6.5 27.6 ± 5.5 < 0.001
C-reactive protein mg/L, median (IQR) 1.9 [0.9–5.0] 2.1 [0.9–4.7] 2.2 [1.1–4.7] 0.37
Urinary albumin-to-creatinine ratio > 30 mg/g, n (%) 14 (5.1) 30 (11.2) 65 (23.6) < 0.001
Estimated glomerular filtration mL/min/1.73 m2 rate < 60§, n (%) 10 (3.6) 25 (9.0) 70 (24.5) < 0.001
Use of hypertensive medication, n (%) 112 (40.4) 128 (45.9) 173 (60.5) < 0.001
Use of statins, n (%) 73 (26.5) 69 (24.9) 78 (27.2) 0.82
Regular use of aspirin, n (%) 97 (35.0) 95 (34.0) 117 (40.6) 0.21
  1. * Characteristics within the cohort random sample; missing values included use of statins (n = 7), use of hypertensive medication (n = 5), estimated glomerular filtration rate (eGFR) (n = 7), baseline diabetes (n = 11), C-reactive protein (n = 23), aspirin use (n = 2), urinary albumin-to-creatinine ratio (n = 32), systolic blood pressure (n = 5), high density lipoprotein (n = 13), cholesterol (n = 7), and body mass index (n = 7). † P-values from analysis of variance for continuous variables and Pearson chi square for categorical variables. ‡ Data weighted to the full cohort for analysis. Tertiles based off of weighted sample. § eGFR < 60 mL/min/1.73 m2 = chronic kidney disease (CKD)