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Table 1 Baseline Characteristics of Study Participants in the Cohort Random Sample by Tertiles of NT-proBNP

From: N-terminal pro-B-type natriuretic peptide and microsize myocardial infarction risk in the reasons for geographic and racial differences in stroke study

 

Brain Natriuretic Peptide (N-terminal pro BNP), tertiles of pg/mL

Characteristics*

< 42.5

42.5–115.5

≥115.5

p-value †

Total participants, n

278 ‡

280‡

289‡

 

Male, n (%)

168 (60.4)

119 (42.5)

101 (35.0)

< 0.001

African American, n (%)

168 (56.8)

129 (46.1)

142 (49.1)

0.03

Age in years, mean (SD)

59.7 ± 9.5

65.9 ± 11.2

74.5 ± 10.9

< 0.001

Less than High School education, n (%)

28 (10.1)

38 (13.6)

61 (21.1)

0.001

Annual Income, n (%)

   

0.001

  < $20,000

38 (13.7)

46 (16.4)

71(24.6)

 ≥$20,000

208 (74.8)

193 (68.9)

157 (54.3)

 Declined to report

32 (11.5)

41 (14.6)

61 (21.1)

Current smoking, n (%)

46 (16.6)

41 (14.7)

33 (11.5)

0.21

Systolic blood pressure, mmHg, mean (SD)

125 ± 14.8

127 ± 17.4

130.8 ± 18.0

< 0.001

High density lipoprotein, mg/L, mean (SD)

50.0 ± 14.7

53.1 ± 17.0

54.0 ± 18.7

0.005

Total cholesterol, mg/L, mean (SD)

196 ± 41

192 ± 37

186 ± 37

< 0.001

Diabetes, n (%)

52 (19.1)

49 (17.8)

59 (20.6)

0.67

Body mass index, kg/m2, mean (SD)

29.8 ± 5.7

29.1 ± 6.5

27.6 ± 5.5

< 0.001

C-reactive protein mg/L, median (IQR)

1.9 [0.9–5.0]

2.1 [0.9–4.7]

2.2 [1.1–4.7]

0.37

Urinary albumin-to-creatinine ratio > 30 mg/g, n (%)

14 (5.1)

30 (11.2)

65 (23.6)

< 0.001

Estimated glomerular filtration mL/min/1.73 m2 rate < 60§, n (%)

10 (3.6)

25 (9.0)

70 (24.5)

< 0.001

Use of hypertensive medication, n (%)

112 (40.4)

128 (45.9)

173 (60.5)

< 0.001

Use of statins, n (%)

73 (26.5)

69 (24.9)

78 (27.2)

0.82

Regular use of aspirin, n (%)

97 (35.0)

95 (34.0)

117 (40.6)

0.21

  1. * Characteristics within the cohort random sample; missing values included use of statins (n = 7), use of hypertensive medication (n = 5), estimated glomerular filtration rate (eGFR) (n = 7), baseline diabetes (n = 11), C-reactive protein (n = 23), aspirin use (n = 2), urinary albumin-to-creatinine ratio (n = 32), systolic blood pressure (n = 5), high density lipoprotein (n = 13), cholesterol (n = 7), and body mass index (n = 7). † P-values from analysis of variance for continuous variables and Pearson chi square for categorical variables. ‡ Data weighted to the full cohort for analysis. Tertiles based off of weighted sample. § eGFR < 60 mL/min/1.73 m2 = chronic kidney disease (CKD)