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Table 2 Follow-up during and after WCD use

From: Therapy optimization in patients with heart failure: the role of the wearable cardioverter-defibrillator in a real-world setting

Total number of patients All patients Newly diagnosed ICM Newly diagnosed NICM ICD explant Newly diagnosed CMP
  LVEF ≤ 35% LVEF ≤ 35%   LVEF ≥ 35%
n = 105 n = 43 n = 41 n = 15 n = 6
Wearing days, mean ± SD 68.8 ± 50.4 57.8 ± 42.6 69.2 ± 39.6 92.5 ± 87.0 70.2 ± 31.2
Wearing hours/day, mean ± SD 21.5 ± 3.5 21.0 ± 3.8 21.3 ± 3.5 23.1 ± 1.1 22.4 ± 1.7
LVEF % baseline, mean ± SD 28.3 ± 9.8 28.9 ± 6.0 23.3 ± 6.9 32.2 ± 13.3 49.0 ± 7.5
LVEF % end of WCD use, mean ± SD 36.1 ± 11.5 36.3 ± 10.3 34.8 ± 11.1 32.9 ± 13.0 50.8 ± 8.6
(p value of LVEF baseline versus end of WCD use) (p < 0.001) (p < 0.001) (p < 0.001) (p = n.s.) (p = n.s.)
ICD implanted
 Total n (%) 54 (51.4) 21 (48.8) 18 (43.9) 13 (86.7) 2 (33.3)
 Days WCD start to ICD implantation, mean ± SD 103.8 ± 73.7 127.7 ± 84.1 90.0 ± 36.8 94.7 ± 90.3 37.0 ± 18.4
 Single-chamber ICD, n (%) 8 (7.6) 3 (7.0) 4 (9.8) 0 (0) 1 (16.7)
 Dual-chamber ICD, n (%) 4 (3.8) 1 (2.3) 0 (0) 2 (13.3) 1 (16.7)
 CRT-D, n (%) 12 (11.4) 3 (7.0) 5 (12.2) 4 (26.7) 0 (0)
 S-ICD, n (%) 30 (28.6) 14 (32.6) 9 (22.0) 7 (46.7) 0 (0)
No ICD implanted
 Total, n (%) 51 (48.6) 22 (51.2) 23 (56.1) 2 (13.3) 4 (66.7)
 LVEF recovery to > 35%, n (%) 40 (38.1) 19 (44.2) 21 (51.2) 0 (0) 0 (0)
 Transient WCD indication, n (%) 4 (3.8) 0 (0) 0 (0) 0 (0) 4 (33.3)
 Patient refused ICD, n (%) 5 (4.8) 2 (4.7) 2 (4.9) 1 (6.7) 0 (0)
 Death during WCD wear, n (%) 2 (1.9) 1 (2.3) 0 (0) 1 (6.7) 0 (0)
 Arrhythmic death during WCD wear, n (%) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0)
  1. CRT-D = cardiac resynchronization therapy with defibrillator, ICM = ischemic cardiomyopathy, ICD = implantable cardioverter-defibrillator, LVEF = left ventricular ejection fraction, n = number of patients, NICM = non-ischemic cardiomyopathy, SD = standard deviation, S-ICD = subcutaneous ICD, WCD = wearable cardioverter-defibrillator