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Table 1 Patient’s baseline data at prescription of WCD

From: Therapy optimization in patients with heart failure: the role of the wearable cardioverter-defibrillator in a real-world setting

Total number of patients All patients Newly diagnosed ICM Newly diagnosed NICM ICD explant Newly diagnosed CMP
  LVEF ≤ 35% LVEF ≤ 35%   LVEF ≥ 35%
n = 105 n = 43 n = 41 n = 15 n = 6
Age, years, median (range) 60 (26–79) 62 (43–78) 54 (30–78) 62 (29–79) 53 (26–63)
Male sex, n (%)
BMI kg/ m2, mean ± SD
82 (78.1)
28.6 ± 6.6
35 (81.4)
28.2 ± 6.2
28 (68.3)
29.8 ± 7.1
14 (93.3)
28.7 ± 6.7
5 (83.3)
23.5 ± 3.6
Arrhythmias before WCD
 Atrial flutter or fibrillation, n (%) 34 (32.4) 10 (23.3) 15 (36.6) 8 (53.3) 1 (16.7)
 Previous VT/VF/SCD, n (%) 21 (20.0) 6 (14.0) 2 (4.9) 8 (53.3) 5 (83.3)
Conduction Disorders
 LBBB, n (%) 19 (18.1) 3 (7.0) 10 (24.4) 6 (40.0) 0 (0)
Cardiovascular risk factors
 Diabetes, n (%) 29 (27.6) 14 (32.6) 10 (24.4) 4 (26.7) 1 (16.7)
 Hypertension, n (%) 71 (67.6) 38 (88.4) 16 (6.6) 13 (86.7) 4 (66.6)
 Hyperlipidemia, n (%) 62 (59.0) 31 (72.1) 17 (41.5) 12 (80.0) 2 (33.3)
Concomitant diseases
 Kidney Dysfunction, n (%) 20 (19.0) 10 (23.3) 6 (14.6) 3 (20.0) 1 (16.7)
 COPD, n (%) 9 (8.6) 3 (7.0) 3 (7.3) 2 (13.3) 1 (16.7)
NYHA, mean ± SD 2.7 ± 1.2 2.7 ± 1.3 3.0 ± 1.0 2.5 ± 0.9 1.3 ± 0.5
LVEF baseline, mean % ± SD 28.3 ± 9.8 28.9 ± 6.0 23.3 ± 6.9 32.2 ± 13.3 49.0 ± 7.5
Medication
 Betablocker, n (%) 102 (97.1) 41 (95.3) 40 (97.6) 15 (100.0) 6 (100.0)
 ACE-I/ARB, n (%) 97 (92.4) 42 (97.7) 39 (95.1) 11 (73.3) 5 (83.3)
 MRA, n (%) 67 (63.8) 25 (58.1) 35 (85.4) 5 (33.3) 2 (33.3)
 ARNI, n (%) 1 (1.0) 0 (0) 1 (2.4) 0 (0) 0 (0)
 Procoralan, n (%) 6 (5.7) 0 (0) 5 (12.2) 1 (6.7) 0 (0)
 Diuretic, n (%) 71 (67.6) 26 (60.5) 31 (75.6) 12 (80.0) 2 (33.3)
 Amiodarone, n (%) 12 (11.4) 1 (2.3) 5 (12.2) 6 (40.0) 0 (0)
  1. ACE-I = angiotensin converting-enzyme inhibitor, ARB = Angiotensin receptor blocker, ARNI = angiotensin receptor-neprilysin inhibitor, BMI = Body mass index, CABG = coronary artery bypass graft, CMP = cardiomyopathy, COPD = chronic obstructive pulmonary disease, ICD = implantable cardioverter-defibrillator, ICM = ischemic cardiomyopathy, LBBB = left bundle branch block, LVEF = left ventricular ejection fraction, MRA = mineralocorticoid receptor antagonist, n = number of patients, NICM = non-ischemic cardiomyopathy, PCI = percutaneous coronary intervention, RBBB = right bundle branch block, SCD = sudden cardiac death, SD = standard deviation, VT = ventricular tachycardia, VF = ventricular fibrillation, WCD = wearable cardioverter-defibrillator