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Table 1 Patient’s baseline data at prescription of WCD

From: Therapy optimization in patients with heart failure: the role of the wearable cardioverter-defibrillator in a real-world setting

Total number of patients

All patients

Newly diagnosed ICM

Newly diagnosed NICM

ICD explant

Newly diagnosed CMP

 

LVEF ≤ 35%

LVEF ≤ 35%

 

LVEF ≥ 35%

n = 105

n = 43

n = 41

n = 15

n = 6

Age, years, median (range)

60 (26–79)

62 (43–78)

54 (30–78)

62 (29–79)

53 (26–63)

Male sex, n (%)

BMI kg/ m2, mean ± SD

82 (78.1)

28.6 ± 6.6

35 (81.4)

28.2 ± 6.2

28 (68.3)

29.8 ± 7.1

14 (93.3)

28.7 ± 6.7

5 (83.3)

23.5 ± 3.6

Arrhythmias before WCD

 Atrial flutter or fibrillation, n (%)

34 (32.4)

10 (23.3)

15 (36.6)

8 (53.3)

1 (16.7)

 Previous VT/VF/SCD, n (%)

21 (20.0)

6 (14.0)

2 (4.9)

8 (53.3)

5 (83.3)

Conduction Disorders

 LBBB, n (%)

19 (18.1)

3 (7.0)

10 (24.4)

6 (40.0)

0 (0)

Cardiovascular risk factors

 Diabetes, n (%)

29 (27.6)

14 (32.6)

10 (24.4)

4 (26.7)

1 (16.7)

 Hypertension, n (%)

71 (67.6)

38 (88.4)

16 (6.6)

13 (86.7)

4 (66.6)

 Hyperlipidemia, n (%)

62 (59.0)

31 (72.1)

17 (41.5)

12 (80.0)

2 (33.3)

Concomitant diseases

 Kidney Dysfunction, n (%)

20 (19.0)

10 (23.3)

6 (14.6)

3 (20.0)

1 (16.7)

 COPD, n (%)

9 (8.6)

3 (7.0)

3 (7.3)

2 (13.3)

1 (16.7)

NYHA, mean ± SD

2.7 ± 1.2

2.7 ± 1.3

3.0 ± 1.0

2.5 ± 0.9

1.3 ± 0.5

LVEF baseline, mean % ± SD

28.3 ± 9.8

28.9 ± 6.0

23.3 ± 6.9

32.2 ± 13.3

49.0 ± 7.5

Medication

 Betablocker, n (%)

102 (97.1)

41 (95.3)

40 (97.6)

15 (100.0)

6 (100.0)

 ACE-I/ARB, n (%)

97 (92.4)

42 (97.7)

39 (95.1)

11 (73.3)

5 (83.3)

 MRA, n (%)

67 (63.8)

25 (58.1)

35 (85.4)

5 (33.3)

2 (33.3)

 ARNI, n (%)

1 (1.0)

0 (0)

1 (2.4)

0 (0)

0 (0)

 Procoralan, n (%)

6 (5.7)

0 (0)

5 (12.2)

1 (6.7)

0 (0)

 Diuretic, n (%)

71 (67.6)

26 (60.5)

31 (75.6)

12 (80.0)

2 (33.3)

 Amiodarone, n (%)

12 (11.4)

1 (2.3)

5 (12.2)

6 (40.0)

0 (0)

  1. ACE-I = angiotensin converting-enzyme inhibitor, ARB = Angiotensin receptor blocker, ARNI = angiotensin receptor-neprilysin inhibitor, BMI = Body mass index, CABG = coronary artery bypass graft, CMP = cardiomyopathy, COPD = chronic obstructive pulmonary disease, ICD = implantable cardioverter-defibrillator, ICM = ischemic cardiomyopathy, LBBB = left bundle branch block, LVEF = left ventricular ejection fraction, MRA = mineralocorticoid receptor antagonist, n = number of patients, NICM = non-ischemic cardiomyopathy, PCI = percutaneous coronary intervention, RBBB = right bundle branch block, SCD = sudden cardiac death, SD = standard deviation, VT = ventricular tachycardia, VF = ventricular fibrillation, WCD = wearable cardioverter-defibrillator