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Table 2 Cox regression models for long-term mortality following AMI by anemia status (n = 2011)

From: Association between admission anemia and long-term mortality in patients with acute myocardial infarction: results from the MONICA/KORA myocardial infarction registry

  Anemiaa (n = 283) Non-anemiad (n = 1728)
Total Mild anemiab (n = 183) Moderate to severe anemiac (n = 100)
HR [95% CI] p Value HR [95% CI] p Value HR [95% CI] p Value HR [95% CI]
Unadjusted model 3.99 [3.07–5.20] < 0.0001 3.35 [2.45–4.68] <.00001 5.22 [3.64–7.48] < 0.0001 Ref.
Model 1e 3.13 [2.39–4.11] < 0.0001 2.71 [1.95–3.77] < 0.0001 3.94 [3.73–5.68] < 0.0001 Ref.
Model 2f 1.85 [1.37–2.49] < 0.0001 1.74 [1.23–2.45] 0.0017 2.05 [1.37–3.05] 0.0004 Ref.
  1. AMI acute myocardial infarction, CI confidence interval, HR hazard ratio, Ref reference category
  2. a Anemia: Hemoglobin (Hb) concentration of < 12 g/dL in women, Hb concentration of < 13 g/dL in men
  3. b Mild anemia: Hb concentration of 11 g/dL to < 12 g/dL in women, Hb concentration of 11 g/dL to < 13 g/dL in men
  4. c Moderate to severe anemia: Hb concentration of < 11 g/dL in men and women
  5. d Non-anemia: Hb concentration of ≥12 g/dL in women, Hb concentration of ≥13 g/dL in men
  6. e Model 1: Adjusted for age and sex
  7. f Model 2: Model 1 + previous myocardial infarction, angina pectoris, hyperlipidemia, diabetes, stroke, eGFR, heart rate, AMI type (STEMI, NSTEMI, Bundle branch block), left-ventricular ejection fraction (LVEF) < 30%, medications at discharge (evidence-based medications (antiplatelet agents, angiotensin-converting-enzyme inhibitor (ACEI), angiotensin-receptor blocker (ARB), beta-blocker, statins), calcium channel blockers, diuretics), percutaneous coronary intervention (PCI) and any in-hospital complication