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Table 2 Cox regression models for long-term mortality following AMI by anemia status (n = 2011)

From: Association between admission anemia and long-term mortality in patients with acute myocardial infarction: results from the MONICA/KORA myocardial infarction registry

 

Anemiaa (n = 283)

Non-anemiad (n = 1728)

Total

Mild anemiab (n = 183)

Moderate to severe anemiac (n = 100)

HR [95% CI]

p Value

HR [95% CI]

p Value

HR [95% CI]

p Value

HR [95% CI]

Unadjusted model

3.99 [3.07–5.20]

< 0.0001

3.35 [2.45–4.68]

<.00001

5.22 [3.64–7.48]

< 0.0001

Ref.

Model 1e

3.13 [2.39–4.11]

< 0.0001

2.71 [1.95–3.77]

< 0.0001

3.94 [3.73–5.68]

< 0.0001

Ref.

Model 2f

1.85 [1.37–2.49]

< 0.0001

1.74 [1.23–2.45]

0.0017

2.05 [1.37–3.05]

0.0004

Ref.

  1. AMI acute myocardial infarction, CI confidence interval, HR hazard ratio, Ref reference category
  2. a Anemia: Hemoglobin (Hb) concentration of < 12 g/dL in women, Hb concentration of < 13 g/dL in men
  3. b Mild anemia: Hb concentration of 11 g/dL to < 12 g/dL in women, Hb concentration of 11 g/dL to < 13 g/dL in men
  4. c Moderate to severe anemia: Hb concentration of < 11 g/dL in men and women
  5. d Non-anemia: Hb concentration of ≥12 g/dL in women, Hb concentration of ≥13 g/dL in men
  6. e Model 1: Adjusted for age and sex
  7. f Model 2: Model 1 + previous myocardial infarction, angina pectoris, hyperlipidemia, diabetes, stroke, eGFR, heart rate, AMI type (STEMI, NSTEMI, Bundle branch block), left-ventricular ejection fraction (LVEF) < 30%, medications at discharge (evidence-based medications (antiplatelet agents, angiotensin-converting-enzyme inhibitor (ACEI), angiotensin-receptor blocker (ARB), beta-blocker, statins), calcium channel blockers, diuretics), percutaneous coronary intervention (PCI) and any in-hospital complication