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Table 1 Baseline characteristics of 114 patients initially presenting with TTC

From: Clinical outcomes associated with catecholamine use in patients diagnosed with Takotsubo cardiomyopathy

Variables

No catecholamines (n = 93)

catecholamines(n = 21)

p value*

Demographics

 Age, mean ± SD

67.65 ± 11.00

65.00 ± 12.30

0.33

 Male, n (%)

13 (13.97)

6 (28.57)

0.11

Symptoms, n (%)

 Dyspnoe

34 (36.55)

9 (42.85)

0.62

 Chest pain

52 (55.91)

6 (28.57)

0.03

Clinic parameter

 Systolic BP, mmHg

134.96 ± 28.41

116.25 ± 42.32

0.01

 Diastolic BP, mmHg

78.41 ± 13.67

66.55 ± 31.22

0.03

 Heart rate, bpm

98.17 ± 27.64

110.95 ± 22.79

0.05

ECG Data, n (%)

 ST-segment elevation

27 (29.03)

7 (33.33)

0.79

 Inversed T-Waves

83 (89.24)

19 (90.47)

0.74

 PQ-interval

160.67 ± 27.97

160.00 ± 34.38

0.92

 QTc (ms), mean ± SD

484.49 ± 50.83

455.30 ± 52.82

0.02

Stress factor, n (%)

 Emotional sress

28 (30.10)

2 (9.52)

0.05

 Physical stress

50 (53.76)

14 (66.66)

0.33

Laboratory values, mean ± SD

 Troponin I (U/L)

3.20 ± 4.41

6.57 ± 8.46

0.01

 Creatine phosphatkinase (U/L)

721.11 ± 2900.64

323.74 ± 469.71

0.55

 CKMB

37.44 ± 65.08

31.00 ± 23.56

0.77

 C-Reactive protein (mg/l)

42.63 ± 64.25

80.30 ± 126.15

0.06

 Hemoglobin

12.10 ± 1.99

12.29 ± 2.08

0.70

 Creatinine (mg/dl)

1.14 ± 0.76

1.19 ± 0.50

0.79

 GFR < 60 ml/min

25 (26.88)

7 (33.33)

0.59

Echocardiography data, n (%)

 LV EF %

39.67 ± 9.12

32.76 ± 9.09

< 0.01

 Follow-up LV EF %

55.23 ± 7.54

48.63 ± 14.90

< 0.01

 Apical ballooning

64 (68.81)

18 (85.71)

0.15

 Mitral regurgation

50 (53.76)

10 (47.61)

0.63

 Tricspid regurgation

42 (45.16)

7 (33.33)

0.46

 RV-Involvement

17 (18.27)

9 (42.85)

0.02

Medical history, n (%)

 Smoking

30 (32.25)

6 (28.57)

0.80

 Diabetes mellitus

22 (23.65)

4 (19.04)

0.64

 Obesity (BMI > 25 kg/m2)

27 (29.03)

4 (19.04)

0.75

 Hypertension

54 (58.06)

12 (57.14)

1.00

 COPD

19 (20.43)

7 (33.33)

0.25

 Atrial fibrillation

15 (16.12)

6 (28.57)

0.21

 Coronary artery disease

16 (17.20)

6 (28.57)

0.23

 History of malignancy

13 (13.97)

3 (14.28)

0.97

Drugs on admission, n (%)

 Beta-blocker

32 (34.40)

3 (14.28)

0.06

 ACE inhibitor

30 (32.25)

5 (23.80)

0.45

 ASS

24 (25.80)

5 (23.80)

0.87

 Anticoagulation

7 (7.52)

0 (0)

0.19

  1. *p values for the comparison between group 1 and group 2; SD Standard deviation, ECG Electrocardiogram, EF Ejection fraction, BMI body-mass-index, COPD Chronic obstructive pulmonary disease, ACE Angiotensin-convetring-enzyme
  2. EFhochversusnichthoch*Katecholaminpflichtigkeit: 0.000
  3. The bolded indication highlight significant values