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Fig. 3 | BMC Cardiovascular Disorders

Fig. 3

From: Percutaneous closure versus medical therapy for stroke with patent foramen Ovale: a systematic review and meta-analysis

Fig. 3

Transient ischemic attack with device closure versus medical therapy. Gore CLOSURE I = Evaluation of the STARFlex Septal Closure System in Patients with a Stroke and/or Transient Ischemic Attack due to Presumed Paradoxical Embolism; CLOSE = the Patent Foramen Ovale Closure or Anticoagulants versus Antiplatelet Therapy to Prevent Stroke Recurrence; PC = Percutaneous Closure of Patent Foramen Ovale in Cryptogenic Embolism; REDUCE = Gore HELEX Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke or Imaging-Confirmed TIA in Patients with Patent Foramen Ovale; RESPECT = Randomized Evaluation of Recurrent Stroke Comparing PFO Closure to Established Current Standard of Care Treatment

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