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Table 3 Predictors of an infectious condition underlying decompensated HF: multivariate models

From: Is there a C-reactive protein value beyond which one should consider infection as the cause of acute heart failure?

  OR (95% CI) P-value Wald
Age, per year 1.03 (1.01–1.05) 0.01 6.60
hsCRP≥25 mg/L 8.05 (5.24–12.36) < 0.001 90.82
Male sex 0.68 (0.43–1.08) 0.10 2.72
Diabetes mellitus 0.89 (0.72–1.10) 0.27 1.22
Coronary heart disease 0.73 (0.47–1.12) 0.15 2.05
Admission systolic blood pressure, per mmHg 1.00 (0.99–1.00) 0.18 1.77
Haemoglobin, per mmol/L 0.87 (0.74–1.03) 0.11 2.53
BNP per 100 pmol/L 1.02 (0.98–1.06) 0.30 1.09
Leukocytes per 1000 cells/μL 0.90 (0.76–1.06) 0.21 1.58
Neutrophils per 1000 cells/μL 1.32 (1.09–1.60) 0.005 7.88
Monocyte-to-Lymphocyte Ratio 0.96 (0.53–1.74) 0.88 0.02
Glomerular filtration rate per 10 mL/min/1.73 m2 1.08 (0.96–1.21) 0.22 1.48
Left ventricular systolic dysfunction 0.76 (0.48–1.22) 0.26 1.28
  OR (95% CI) P-value  
Age, per year 1.02 (1.00–1.04) 0.02 5.51
hsCRP per 1 mg/L 1.02 (1.01–1.02) < 0.001 44.85
Male sex 0.84 (0.54–1.30) 0.44 0.60
Diabetes mellitus 0.90 (0.73–1.10) 0.31 1.02
Coronary heart disease 0.77 (0.51–1.17) 0.23 1.46
Admission systolic blood pressure, per mmHg 0.99 (0.99–1.00) 0.11 2.51
Haemoglobin, per mmol/L 0.86 (0.73–1.02) 0.08 3.17
BNP per 100 pmol/L 1.01 (0.98–1.05) 0.48 0.50
Leuckoytes per 1000 cells/μL 0.88 (0.72–1.08) 0.22 1.51
Neutrophils per 1000 cells/μL 1.33 (1.06–1.66) 0.01 6.31
Monocyte-to-Lymphocyte Ratio 0.84 (0.45–1.55) 0.57 0.32
Glomerular filtration rate per 10 mL/min/1.73m2 1.05 (0.94–1.17) 0.41 0.67
Left ventricular systolic dysfunction 0.77 (0.49–1.20) 0.25 1.34
  1. BNP B-type natriuretic peptide, CI Confidence Interval, hsCRP high sensitivity C-reactive protein, OR Odds Ratio