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Table 1 Comparison between acute HF patients with and without an infectious condition underlying cardiac decompensation

From: Is there a C-reactive protein value beyond which one should consider infection as the cause of acute heart failure?

Characteristics Non-infected patients (n = 359) Infected patients (n = 256) p-value
Male sex, n (%) 175 (48.7) 103 (40.2) 0.04
Age, mean (SD) 75 (12) 79 (11) < 0.001
Atrial fibrillation, n (%) 173 (48.2) 107 (41.8) 0.12
Diabetes mellitus, n (%) 159 (44.3) 94 (36.7) 0.06
Coronary heart disease, n (%) 159 (44.4) 92 (36.0) 0.04
Admission NYHA IV (vs II/III) 209 (58.2) 162 (63.3) 0.29
Admission heart rate (bpm), mean (SD) 90 (25) 88 (21) 0.34
Admission systolic blood pressure (mmHg), mean (SD) 136 (31) 130 (28) 0.01
Left ventricular systolic dysfunction, n (%) 234 (65.1) 137 (53.5) 0.003
Haemoglobin (mmol/L), mean (SD) 7.4 (1.4) 7.1 (1.3) 0.001
Leukocytes (cells/μL) 7934 (3056) 9704 (4122) < 0.001
Neutrophils (cells/μL) 5774 (2511) 7733 (3815) < 0.001
Monocyte-to-Lymphocyte Ratio, mean (SD) 0.54 (0.37) 0.65 (0.40) 0.001
Glomerular filtration rate (mL/min/1.73m2) 48.3 (20.9) 44.9 (20.7) 0.05
C-reactive protein (mg/L), median (IQR) 12.8 (7.1–24.2) 53.1 (22.8–116.0) < 0.001
C-reactive protein ≥25 mg/L 82 (22.8) 186 (72.7) < 0.001
BNP (pmol/L), median (IQR) 458.8 (257.2–783.5) 547.4 (293.7–858.1) 0.08
Acetylsalicylic acid, n (%) 174 (48.5) 119 (46.5) 0.65
Statin, n (%) 188 (52.4) 120 (46.9) 0.19
1-year death 130 (36.2) 102 (39.8) 0.36
  1. BNP B-type natriuretic peptide, hsCRP high sensitivity C-reactive protein, IQR interquartile range, NYHA New York Heart Association, SD standard deviation