Table 1 Comparison between acute HF patients with and without an infectious condition underlying cardiac decompensation
Characteristics | Non-infected patients (n = 359) | Infected patients (n = 256) | p-value |
|---|---|---|---|
Male sex, n (%) | 175 (48.7) | 103 (40.2) | 0.04 |
Age, mean (SD) | 75 (12) | 79 (11) | < 0.001 |
Atrial fibrillation, n (%) | 173 (48.2) | 107 (41.8) | 0.12 |
Diabetes mellitus, n (%) | 159 (44.3) | 94 (36.7) | 0.06 |
Coronary heart disease, n (%) | 159 (44.4) | 92 (36.0) | 0.04 |
Admission NYHA IV (vs II/III) | 209 (58.2) | 162 (63.3) | 0.29 |
Admission heart rate (bpm), mean (SD) | 90 (25) | 88 (21) | 0.34 |
Admission systolic blood pressure (mmHg), mean (SD) | 136 (31) | 130 (28) | 0.01 |
Left ventricular systolic dysfunction, n (%) | 234 (65.1) | 137 (53.5) | 0.003 |
Haemoglobin (mmol/L), mean (SD) | 7.4 (1.4) | 7.1 (1.3) | 0.001 |
Leukocytes (cells/μL) | 7934 (3056) | 9704 (4122) | < 0.001 |
Neutrophils (cells/μL) | 5774 (2511) | 7733 (3815) | < 0.001 |
Monocyte-to-Lymphocyte Ratio, mean (SD) | 0.54 (0.37) | 0.65 (0.40) | 0.001 |
Glomerular filtration rate (mL/min/1.73m2) | 48.3 (20.9) | 44.9 (20.7) | 0.05 |
C-reactive protein (mg/L), median (IQR) | 12.8 (7.1–24.2) | 53.1 (22.8–116.0) | < 0.001 |
C-reactive protein ≥25 mg/L | 82 (22.8) | 186 (72.7) | < 0.001 |
BNP (pmol/L), median (IQR) | 458.8 (257.2–783.5) | 547.4 (293.7–858.1) | 0.08 |
Acetylsalicylic acid, n (%) | 174 (48.5) | 119 (46.5) | 0.65 |
Statin, n (%) | 188 (52.4) | 120 (46.9) | 0.19 |
1-year death | 130 (36.2) | 102 (39.8) | 0.36 |