Table 1 Alteration of the risk factors used for the calculation of Framingham Risk Score in 35 eligible studies compared to the Framingham Risk Score 1998, 2002 and 2008
|  | No. of Studies (n = 35) | ||
|---|---|---|---|
Ordinal outcomes | |||
Items of Alteration (n = 18) | Yes | No | Unclear |
Addition | Â | Â | Â |
Item 1. Antihypertensive | 16 | 15 | 4 |
Item 2. Weight related measures, e.g. BMI | 0 | 35 | 0 |
Item 3. Race/ethnic groups | 2 | 33 | 0 |
Item 4. Triglycerides | 2 | 33 | 0 |
Item 5. Alcohol | 0 | 35 | 0 |
Item 6. Previous cardiovascular disease | 1 | 34 | 0 |
Item 7. Others (family history, PVD & stroke) | 5 | 30 | 0 |
Deletion | Â | Â | Â |
Item 8. Diastolic blood pressure | 9 | 21 | 5 |
Item 9. aDiabetes | 0 | 19 | 0 |
Item 10. HDL cholesterol | 4 | 28 | 3 |
Modification | Â | Â | Â |
Blood pressure | Â | Â | Â |
Item 11. Systolic blood pressure | 3 | 23 | 9 |
Item 12. History of hypertension/self-reported hypertension | 7 | 23 | 5 |
Item 13. Other blood pressure definition modification | 3 | 31 | 1 |
Lipid levels | Â | Â | Â |
Item 14. History of hyperlipidaemia/ self-reported hyperlipidaemia | 14 | 14 | 7 |
Diabetes | Â | Â | Â |
Item 15. aFasting glucose > 126 mg/dL or 7.8 mmol/L | 0 | 19 | 0 |
Item 16. aSelf-reported diabetes/ use diabetic medication | 3 | 10 | 6 |
Smoking | Â | Â | Â |
Item 17. Pack years of smoking | 0 | 34 | 1 |
Item 18. Use of ex-smoker category | 11 | 23 | 1 |