Skip to main content

Table 1 Clinical characteristics of the study groups (n = 234)

From: Association between brain-derived neurotrophic factor and von Willebrand factor levels in patients with stable coronary artery disease

  Overall Stable CAD (n = 143) Non-CAD (n = 91) p value
Age, years 65.9 ± 10.5 67.9 ± 10.3 62.8 ± 10.2 < 0.001
Gender, male, n (%) 153 (65.4) 104 (72.7) 49 (53.8) 0.003
BMI (kg/m2) 24.1 ± 2.4 24.2 ± 2.5 23.9 ± 2.4 0.450
Smoking, n (%) 102 (43.6) 68 (47.6) 34 (37.4) 0.125
SBP (mmHg) 136 ± 15 135 ± 15 137 ± 14 0.340
DBP (mmHg) 82 ± 11 81 ± 10 83 ± 12 0.161
Triglycerides (mmol/L) 1.62 (1.23–2.20) 1.65 (1.26–2.20) 1.57 (1.09–2.20) 0.266
TC (mmol/L) 4.54 ± 1.03 4.66 ± 1.07 4.36 ± 0.94 0.031
LDL cholesterol (mmol/L) 2.60 ± 0.83 2.67 ± 0.91 2.49 ± 0.68 0.102
HDL cholesterol (mmol/L) 1.18 ± 0.28 1.15 ± 0.29 1.21 ± 0.26 0.082
Platelet count(× 104/μl) 185 (166–217) 183 (154–216) 196 (167–230) 0.099
Creatinine (μmol/L) 76 (65–87) 76 (66–89) 73 (62–81) 0.067
Glucose (mmol/L) 5.5 (4.9–6.9) 5.7 (5.0–7.2) 5.4 (4.8–6.7) 0.162
Diabetes mellitus, n (%) 79 (33.8) 58 (59.4) 21 (23.1) 0.006
Hypertension, n (%) 156 (66.7) 107 (74.8) 49 (53.8) 0.001
Medication use, n (%)
 Aspirin 68 (29.1) 44 (30.8) 24 (26.4) 0.566
 Beta-blocker 68 (29.1) 41 (28.7) 27 (29.7) 0.987
 Statin 55 (23.5) 34 (23.8) 21 (23.1) 0.902
 ACEI/ARB 95 (40.6) 59 (41.3) 36 (39.6) 0.903
 CCB 104 (44.4) 64 (44.8) 40 (44.0) 0.905
CRP (mg/L) 1.17 (0.67–2.20) 1.23 (0.69–2.20) 0.93 (0.61–2.21) 0.079
vWF (IU/dl) 102 ± 26 111 ± 27 89 ± 18 < 0.001
BDNF (pg/ml) 1187 (784–1543) 937 (679–1263) 1361 (884–1846) < 0.001
  1. Values are shown as the means ± SD, median (interquartile range) or percentage. CAD coronary artery disease, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, TC total cholesterol, LDL low-density lipoprotein, HDL high-density lipoprotein, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker, CCB calcium channel blocker, CRP C-reactive protein, vWF von Willebrand factor, BDNF brain-derived neurotrophic factor
\