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Table 1 Clinical characteristics of the study groups (n = 234)

From: Association between brain-derived neurotrophic factor and von Willebrand factor levels in patients with stable coronary artery disease

 

Overall

Stable CAD (n = 143)

Non-CAD (n = 91)

p value

Age, years

65.9 ± 10.5

67.9 ± 10.3

62.8 ± 10.2

< 0.001

Gender, male, n (%)

153 (65.4)

104 (72.7)

49 (53.8)

0.003

BMI (kg/m2)

24.1 ± 2.4

24.2 ± 2.5

23.9 ± 2.4

0.450

Smoking, n (%)

102 (43.6)

68 (47.6)

34 (37.4)

0.125

SBP (mmHg)

136 ± 15

135 ± 15

137 ± 14

0.340

DBP (mmHg)

82 ± 11

81 ± 10

83 ± 12

0.161

Triglycerides (mmol/L)

1.62 (1.23–2.20)

1.65 (1.26–2.20)

1.57 (1.09–2.20)

0.266

TC (mmol/L)

4.54 ± 1.03

4.66 ± 1.07

4.36 ± 0.94

0.031

LDL cholesterol (mmol/L)

2.60 ± 0.83

2.67 ± 0.91

2.49 ± 0.68

0.102

HDL cholesterol (mmol/L)

1.18 ± 0.28

1.15 ± 0.29

1.21 ± 0.26

0.082

Platelet count(× 104/μl)

185 (166–217)

183 (154–216)

196 (167–230)

0.099

Creatinine (μmol/L)

76 (65–87)

76 (66–89)

73 (62–81)

0.067

Glucose (mmol/L)

5.5 (4.9–6.9)

5.7 (5.0–7.2)

5.4 (4.8–6.7)

0.162

Diabetes mellitus, n (%)

79 (33.8)

58 (59.4)

21 (23.1)

0.006

Hypertension, n (%)

156 (66.7)

107 (74.8)

49 (53.8)

0.001

Medication use, n (%)

 Aspirin

68 (29.1)

44 (30.8)

24 (26.4)

0.566

 Beta-blocker

68 (29.1)

41 (28.7)

27 (29.7)

0.987

 Statin

55 (23.5)

34 (23.8)

21 (23.1)

0.902

 ACEI/ARB

95 (40.6)

59 (41.3)

36 (39.6)

0.903

 CCB

104 (44.4)

64 (44.8)

40 (44.0)

0.905

CRP (mg/L)

1.17 (0.67–2.20)

1.23 (0.69–2.20)

0.93 (0.61–2.21)

0.079

vWF (IU/dl)

102 ± 26

111 ± 27

89 ± 18

< 0.001

BDNF (pg/ml)

1187 (784–1543)

937 (679–1263)

1361 (884–1846)

< 0.001

  1. Values are shown as the means ± SD, median (interquartile range) or percentage. CAD coronary artery disease, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, TC total cholesterol, LDL low-density lipoprotein, HDL high-density lipoprotein, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker, CCB calcium channel blocker, CRP C-reactive protein, vWF von Willebrand factor, BDNF brain-derived neurotrophic factor