Early commitment of cardiovascular autonomic modulation in Brazilian patients with congenital generalized lipodystrophy

Table 4 Correlations between cardiovascular autonomic tests and metabolic parameters of patients with CGL and healthy individuals

n = 30		30/15	Valsalva	E/I	VLF	LF	HF	Total espectrum
Age	r	0.155	−0.245	−0.190	−0.029	−0.128	−0.275	−0.181
Age	p	0.412	0.191	0.313	0.876	0.499	0.142	0.337
BMI	r	0.034	−0.182	−0.447	−0.201	−0.315	−0.436	−0.405
BMI	p	0.860	0.335	0.013	0.287	0.090	0.016	0.026
Fasting glycemia	r	−0.204	−0.184	−0.253	−0.488	−0.313	−0.259	−0.311
Fasting glycemia	p	0.280	0.330	0.178	0.006	0.093	0.167	0.095
A1c	r	−0.400	−0.190	−0.310	−0.460	−0.525	−0.326	−0.434
A1c	p	0.029	0.315	0.096	0.010	0.003	0.079	0.017
Basal Insulin	r	−0.432	−0.358	−0.610	−0.501	−0.590	−0.645	−0.583
Basal Insulin	p	0.017	0.052	0.000	0.005	0.001	0.000	0.001
HOMA-IR	r	−0.439	−0.362	−0.591	−0.543	−0.561	−0.598	−0.555
HOMA-IR	p	0.015	0.049	0.001	0.002	0.001	0.000	0.001
Leptin	r	0.537	0.312	0.291	0.338	0.339	0.379	0.364
Leptin	p	0.002	0.094	0.119	0.067	0.067	0.039	0.048
ACR	r	−0.514	−0.200	−0.356	−0.627	−0.374	−0.276	−0.477
ACR	p	0.004	0.289	0.053	0.000	0.042	0.140	0.008
Total cholesterol	r	−0.259	−0.021	−0.262	−0.103	−0.193	−0.145	−0.156
Total cholesterol	p	0.167	0.913	0.161	0.589	0.306	0.444	0.411
HDL-c	r	0.366	0.248	0.301	0.313	0.198	0.199	0.221
HDL-c	p	0.046	0.186	0.106	0.092	0.294	0.292	0.240
LDL-c	r	−0.259	0.058	−0.214	−0.027	−0.079	−0.123	−0.077
LDL-c	p	0.184	0.769	0.275	0.892	0.688	0.532	0.698
Triglycerides	r	−0.632	−0.261	−0.674	−0.470	−0.548	−0.420	−0.539
Triglycerides	p	0.000	0.163	0.000	0.009	0.002	0.021	0.002

CGL congenital generalized lipodystrophy, BMI body mass index, A1c glycated hemoglobin, HOMA-IR Homeostasis model assessment-insulin resistance, HDL high-density lipoprotein, LDL low-density lipoprotein, ACR albumin/creatinine ratio, 30/15 orthostatic coefficient, E/I respiratory coefficient, VLF very low frequency, LF low frequency, HF high frequency. Test: Spearman’s correlation posts. Significance p < 0.050 are marked in italic

ISSN: 1471-2261