Effects of angiotensin receptor blockers on neointimal characteristics in angina patients requiring stent implantation: optical coherence tomography analysis

Table 5 Secondary endpoint. Cardiovascular events, QCA measurements and quantitative OCT findings during the follow-up period

Cardiovascular events	ARB Group (n = 162)	Non-ARB Group (n = 245)	P value
Cardiovascular Events
Non-fatal MI	3 (1.9%)	2 (0.8%)	0.354
Cardiac death	1 (0.6%)	0	0.319
Stroke	0	0	1.000
TLR	25 (15.4%)	23 (9.4%)	0.077
QCA measurements
Angiographic follow-up duration (months)	19.0 ± 11.4	20.3 ± 14.1	0.523
RD (mm)	2.66 ± 0.30	2.68 ± 0.34	0.543
MLD (mm)	2.24 ± 0.29	2.21 ± 0.27	0.648
% stenosis	16 ± 8	19 ± 12	0.321
Late lumen loss (mm)	0.29 ± 0.28	0.32 ± 0.36	0.196
Binary restenosis	14 (8.6%)	22 (9.0%)	0.465
Quantitative OCT findings
Mean lumen area, mm²	6.40 ± 2.49	6.74 ± 2.18	0.318
Mean neointimal area, mm²	1.09 ± 1.00	1.38 ± 1.24	0.096
Mean neointimal thickness, μm	140.6 ± 112.0	189.6 ± 423.1	0.217
Malapposed strut No, %	0.70%	1.00%	0.322
Exposed strut No, %	0.80%	1.10%	0.372
Covered strut No, %	97.30%	92.60%	0.015

MI myocardial infarction, TLR target lesion restenosis, QCA quantitative coronary angiography, RD reference diameter, MLD minimal lumen diameter, OCT optical coherence tomography, No numbers
Values are expressed as mean ± SD for quantitative variables or as n (%) for qualitative variables

ISSN: 1471-2261