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Table 2 Baseline and Post-Treatment/Placebo Laboratory Parameters

From: Vitamin D3 repletion versus placebo as adjunctive treatment of heart failure patient quality of life and hormonal indices: a randomized, double-blind, placebo-controlled trial

  Placebo Baseline Placebo 6 months Treatment Baseline Treatment
6 months
p-value
Baseline
p-value
6 months
Sodium (mEq/L) 140 ± 2 140 ± 3 138 ± 3 139 ± 2 0.11 0.24
Chloride 104 ± 4 104 ± 3 99 ± 21 104 ± 3 0.25 0.25
Co2 26.3 ± 2.9 25.8 ± 2.1 25.0 ± 3.0 25.5 ± 3.0 0.46 0.86
Potassium(mEq/L) 4.1 ± 0.8 4.1 ± 0.3 4.4 ± 0.3 4.3 ± 0.4 0.29 0.15
BUN (mg/dl) 22 ± 12 23 ± 13 24 ± 10 27 ± 13 0.46 0.33
Creatinine 1.3 ± 0.6 1.3 ± 0.6 1.2 ± 0.4 1.3 ± 0.5 0.29 0.86
Glucose (mg/dl) 115 ± 41 105 ± 36 118 ± 35 108 ± 23 0.64 0.79
Calcium (mg/dl) 8.9 ± 0.5 8.9 ± 0.8 9.0 ± 0.4 9.2 ± 0.4 0.71 0.18
Hemoglobin (g/dl) 14.1 ± 1.9 13.9 ± 1.5 14 ± 6.2 13.4 ± 1.5 0.63 0.51
Hematocrit (%) 44.5 ± 12.8 41.5 ± 4.4 42.6 ± 11.0 40 ± 4.6 0.39 0.31
BNP (pg/ml) 1800 ± 400 2300 ± 950 1600 ± 550 1400 ± 600 0.43 0.31
PTH (pg/ml) 90 ± 96* 93 ± 112 58 ± 28 45 ± 19 0.002 0.002
hsCRP (mg/ml) 3.5 ± 3.1 4.4 ± 3.9 5.4 ± 5.5 3.8 ± 1.1 0.42 0.18
25(OH)D (ng/ml) 20 ± 7 20 ± 9 19 ± 7 70 ± 28 0.8 0.001
  1. Data are expressed as mean absolute values + standard deviation (SD). Abbreviations: Blood Urea Nitrogen (BUN), B-type Natriuretic Peptide (BNP), Parathyroid Hormone (PTH), high-sensitivity c-reactive protein (hsCRP), and 25-hydroxyvitamin D (25(OH)D)
  2. *Indicates significant difference in PTH between placebo and treatment group at baseline, p=0.002