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Table 3 Comparison of clinical and biochemical data between patients with limited exercise vs. preserved exercise capacity (6-min walk distance)

From: Quality of life questionnaire predicts poor exercise capacity only in HFpEF and not in HFrEF

Variable 6MWT > 300 m 6MWT <300 m P value
  (n = 76) (n = 42)  
Age (years) 60 ± 9.5 66 ± 9 0.003
Smoking (%) 28 33 0.516
Diabetes (%) 20 41 0.015
Arterial hypertension (%) 66 69 0.839
LBBB (%) 10 21 0.169
Waist/hips ratio 0.95 ± 0.1 0.98 ± 0.1 0.036
BMI (kg/m2) 29 ± 4.1 28 ± 3.8 0.730
BSA (m2) 1.2 ± 0.2 1.1 ± 0.2 0.046
NYHA class    0.002a
NYHA class I, II, III (%) 38, 47, 15 14, 45, 41  
HFpEF (%) 46 57 0.249
Fasting glucose (mmol/L) 6.4 ± 2.5 7.8 ± 2.9 0.013
Creatinine (μmol/L) 97.6 ± 54 93.0 ± 21 0.604
Hemoglobin (g/dL) 12.7 ± 1.6 12.3 ± 2.0 0.203
HR (beats/min) 72 ± 15 80 ± 13 0.006
NT-ProBNP (pg/mL 1510 ± 4146 1832 ± 2907 0.66
MLHFQ total 43.8 ± 16.9 56.9 ± 14.4 <0.001
MLHFQ physical 22.1 ± 9 27.6 ± 6.9 0.001
MLHFQ emotional 8.0 ± 4.3 10.9 ± 4.3 0.001
  1. BMI body mass index, BSA body surface area, HR heart rate, NYHA New York heart association, LBBB left bundle branch block, NT-ProBNP N-terminal pro b-type natriuretic peptide, HFpEF heart failure with a preserved ejection fraction, MLHFQ minnesota living with heart failure questionnaire
  2. aNYHA class significance between study groups