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Table 3 Comparison of clinical and biochemical data between patients with limited exercise vs. preserved exercise capacity (6-min walk distance)

From: Quality of life questionnaire predicts poor exercise capacity only in HFpEF and not in HFrEF

Variable

6MWT > 300 m

6MWT <300 m

P value

 

(n = 76)

(n = 42)

 

Age (years)

60 ± 9.5

66 ± 9

0.003

Smoking (%)

28

33

0.516

Diabetes (%)

20

41

0.015

Arterial hypertension (%)

66

69

0.839

LBBB (%)

10

21

0.169

Waist/hips ratio

0.95 ± 0.1

0.98 ± 0.1

0.036

BMI (kg/m2)

29 ± 4.1

28 ± 3.8

0.730

BSA (m2)

1.2 ± 0.2

1.1 ± 0.2

0.046

NYHA class

  

0.002a

NYHA class I, II, III (%)

38, 47, 15

14, 45, 41

 

HFpEF (%)

46

57

0.249

Fasting glucose (mmol/L)

6.4 ± 2.5

7.8 ± 2.9

0.013

Creatinine (μmol/L)

97.6 ± 54

93.0 ± 21

0.604

Hemoglobin (g/dL)

12.7 ± 1.6

12.3 ± 2.0

0.203

HR (beats/min)

72 ± 15

80 ± 13

0.006

NT-ProBNP (pg/mL

1510 ± 4146

1832 ± 2907

0.66

MLHFQ total

43.8 ± 16.9

56.9 ± 14.4

<0.001

MLHFQ physical

22.1 ± 9

27.6 ± 6.9

0.001

MLHFQ emotional

8.0 ± 4.3

10.9 ± 4.3

0.001

  1. BMI body mass index, BSA body surface area, HR heart rate, NYHA New York heart association, LBBB left bundle branch block, NT-ProBNP N-terminal pro b-type natriuretic peptide, HFpEF heart failure with a preserved ejection fraction, MLHFQ minnesota living with heart failure questionnaire
  2. aNYHA class significance between study groups