Fig. 5

AAA Quantification in chimeric LDLr^−/− mice with macrophage-deletion of NOR1. Mice were prepared as indicated in Fig. 3. Recipient LDLr^−/− mice transplanted with wild-type or NOR1-deficient bone marrow-derived cells were referred to as NOR^+/+➔LDLr^−/− or NOR1^−/− ➔ LDLr^−/−, respectively a. In vivo measurements of suprarenal aorta lumen diameter by ultrasound (U/S) on day 0 and 28 of angiotensin II infusion. Black circles (NOR1^+/+ donors, n = 13) and white circles (NOR1^−/− donors, n = 11) represent measurements in individual mice; diamonds represent the means for each group, and bars indicate SEM. b. Representative images of abdominal aorta ultrasound measurements in LDLr^−/− mice with wild-type or NOR1-deficient bone marrow transplantation on 0 day and 28 day of angiotensin II (Ang II) infusion. c. Ex vivo measurements of the maximal external diameter of suprarenal aorta acquired at termination after 28 days of angiotensin II infusion. Black circles (NOR1^+/+ donors, n = 13) and white circles (NOR1^−/− donors, n = 11) represent measurements in individual mice; diamonds represent the average for each group, and bars indicate SEM