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Table 1 All ARVD/C, ARVD/C with (+ECG) and without (−ECG) 2010 ECG taskforce criteria

From: Right precordial-directed electrocardiographical markers identify arrhythmogenic right ventricular cardiomyopathy in the absence of conventional depolarization or repolarization abnormalities

 

ARVC Total (N = 155)

ECG-positive ARVC (N = 89)

ECG-negative ARVC (N = 66)

p-value

ECG-positive vs ECG-negative

Age

42.1 ± 17.3

42.0 ± 17.4

41.7 ± 17.6

0.861

Sex (% male)

106 (68.4%)

63 (70.8%)

43 (65.2%)

0.488

Proband (%)

111 (71.6%)

71 (79.8%)

30 (45.5%)

0.012

I. Imaging

155 (100%)

89 (100%)

66 (100%)

1.000

 major, %

111 (71.6%)

68 (76.4%)

43 (65.2%)

0.082

 minor, %

89 (57.4%)

60 (67.4%)

29 (43.9%)

0.005

II. Tissue characterization of the wall, biopsies performed (% of patients)

70 (45.2%)

39 (43.8%)

31 (47.0%)

0.745

 major, %

53 (75.7%)

31 (79.1%)

22 (71.0%)

0.576

 minor, %

63 (90.0%)

36 (92.3%)

27 (87.1%)

0.454

III. Repolarization abnormality

    

 major, %

54 (34.8%)

54 (60.7%)

0 (0.0%)

<0.001

 minor, %

20 (12.9%)

20 (22.5%)

0 (0.0%)

<0.001

IV. Depolarization abnormality

    

 major, %

13 (8.4%)

13 (14.6%)

0 (0.0%)

<0.001

 minor, %

17 (11.0%)

17 (19.1%)

0 (0.0%)

<0.001

V. Arrhythmia

    

 major, %

44 (28.4%)

26 (29.2%)

18 (27.3%)

0.858

 minor, %

64 (41.3%)

42 (47.2%)

22 (33.3%)

0.1000

VI. Family history

    

 major, %

84 (54.2%)

48 (53.9%)

35 (53.0%)

1.000

VII. Genotype positive

48 (31.0%)

29 (32.6%)

19 (28.8%)

0.726

 PLN (% genotype positive)

1 (2.1%)

0 (0.0%)

1 (5.3%)

0.396

 TTN (% genotype positive)

11 (22.9%)

8 (27.6%)

3 (15.8%)

0.488

 PKP2 (% genotype positive)

23 (47.9%)

17 (58.6%)

6 (31.2%)

0.083

 DSC2 (% genotype positive)

2 (4.2%)

1 (3.5%)

1 (5.3%)

1.000

 DSG2 (% genotype positive)

12 (25.0%)

6 (20.7%)

6 (31.5%)

0.501

 DSG3 (% genotype positive)

2 (4.2%)

1 (3.5%)

1 (5.30%)

1.000

 DSP (% genotype positive)

8 (16.7%)

6 (20.7%)

2 (10.56%)

0.4510