Table 3 Predictors of medication nonadherence
All Drugs (Dabigatran reference drug) | Dabigatran | Rivaroxaban | Apixaban | |
|---|---|---|---|---|
Parameter | Odds Ratio (95% CI) | Odds Ratio (95% CI) | Odds Ratio (95% CI) | Odds Ratio (95% CI) |
Age | 0.98 (0.96, 0.99) | 0.99 (0.97, 1.00) | 0.96 (0.93, 0.99) | 0.97 (0.90, 1.04) |
Male | 0.85 (0.54, 1.34) | 0.85 (0.47, 1.53) | 1.58 (0.54, 4.61) | 0.26 (0.06, 1.13) |
White Race | 0.73 (0.59, 0.92) | 0.69 (0.53, 0.90) | 0.81 (0.48, 1.37) | 0.61 (0.23, 1.65) |
Hypertension | 0.69 (0.49, 0.99) | 0.74 (0.47, 1.16) | 0.64 (0.27, 1.50) | 0.66 (0.17, 2.61) |
Congestive Heart Failure | 0.74 (0.53, 1.03) | 0.91 (0.61, 1.36) | 0.52 (0.24, 1.13) | 0.28 (0.07, 1.10) |
Diabetes Mellitus | 0.57 (0.41, 0.79) | 0.68 (0.47, 0.97) | 0.56 (0.27, 1.14) | 0.15 (0.03, 0.67) |
CVA | 0.36 (0.20, 0.68) | 0.47 (0.23, 0.94) | 0.29 (0.06, 1.40) | 0.11 (0.01, 1.43) |
Prior Myocardial Infarction | 1.20 (0.96, 1.50) | 1.40 (1.07, 1.82) | 0.88 (0.55, 1.39) | 0.53 (0.18, 1.53) |
Peripheral Arterial Disease | 0.99 (0.72, 1.36) | 0.96 (0.68, 1.34) | 1.14 (0.60, 2.17) | 1.32 (0.49, 3.54) |
CHA2DS2-VASc Score | 0.88 (0.76, 1.01) | 0.81 (0.68, 0.97) | 1.09 (0.85, 1.41) | 0.81 (0.40, 1.64) |