Characteristics | Adults (n = 6689) | Elderly (n = 6689) | Very elderly (n = 6689) | |||
---|---|---|---|---|---|---|
aHR | 95% CI | aHR | 95% CI | aHR | 95% CI | |
Sex | ||||||
Male (reference) | 1.00 | 1.00 | 1.00 | |||
Female | 0.90 | 0.82–0.98 | 0.92 | 0.84–1.01 | 0.85 | 0.78–0.93 |
Charlson comorbidity index score | ||||||
0 (reference) | 1.00 | 1.00 | 1.00 | |||
≥ 1 | 0.95 | 0.87–1.03 | 0.98 | 0.92–1.04 | 0.93 | 0.87–0.98 |
Health insurance type | ||||||
Health insurance (reference) | 1.00 | 1.00 | 1.00 | |||
Medical aid | 1.21 | 1.06–1.39 | 1.07 | 0.92–1.26 | 0.83 | 0.71–0.98 |
Underlying disease risk factor | ||||||
Dementia | 1.66 | 0.93–2.97 | 1.15 | 0.75–1.77 | 0.68 | 0.52–0.90 |
Depression | 1.11 | 0.95–1.28 | 1.36 | 1.00–1.85 | 0.91 | 0.63–1.32 |
Dyslipidaemia | 0.64 | 0.59–0.71 | 0.75 | 0.61–0.92 | 0.75 | 0.57–0.98 |
Therapeutic class of index therapy | ||||||
Angiotensin receptor blockers (reference) | 1.00 | 1.00 | 1.00 | |||
Dihydropyridine calcium channel blockers | 1.12 | 1.02–1.22 | 1.03 | 0.93–1.13 | 1.04 | 0.94–1.14 |
Selective beta blockers | 1.93 | 1.73–2.16 | 1.58 | 1.37–1.82 | 1.29 | 1.11–1.51 |
Thiazide diuretics | 4.04 | 3.49–4.67 | 2.87 | 2.48–3.33 | 1.74 | 1.51–2.02 |
Alpha blockers | 1.90 | 1.15–3.15 | 1.23 | 0.92–1.65 | 1.03 | 0.81–1.30 |
Angiotensin converting enzyme inhibitors | 1.42 | 1.03–1.97 | 1.14 | 0.77–1.68 | 0.96 | 0.68–1.37 |
Others | 2.39 | 1.18–4.88 |