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Table 2 Comparison of treatment persistence and adherence among propensity-matched cohorts

From: Persistence with antihypertensives in uncomplicated treatment-naïve very elderly patients: a nationwide population-based study

Variables

Adults a (n = 6689)

Elderly b (n = 6689)

Very elderly c (n = 6689)

p-value*

Post hoc

Treatment duration, days, mean (SD)

277.1 (122.8)

280.6 (123.3)

267.6 (127.2)

<0.0001

a,b > c

Treatment persistence rate, n (%)

 at the first 3 months

5753 (86.0)

5764 (86.2)

5663 (84.7)

0.024

b > c

 at the first 6 months

4731 (70.7)

4754 (71.1)

4473 (66.9)

<0.0001

a, b > c

 at the first 9 months

4422 (66.1)

4532 (67.8)

4207 (62.9)

<0.0001

a, b > c

 at the first 12 months

4179 (62.5)

4364 (65.2)

3979 (59.5)

<0.0001

b > a > c

Medication possession ratio, mean (SD)

0.76 (0.30)

0.79 (0.29)

0.75 (0.30)

<0.0001

b > a, c

Treatment adherence rate, n (%)

4290 (64.1)

4542 (67.9)

4135 (62.8)

<0.0001

b > a > c

  1. *Analysis of variance test or chi-squared test of the three groups
  2. Bonferroni correction (p < 0.015) with student’s t-test or chi-squared test
  3. aAdult cohort bElderly cohort cVery elderly cohort