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Table 2 Comparison of treatment persistence and adherence among propensity-matched cohorts

From: Persistence with antihypertensives in uncomplicated treatment-naïve very elderly patients: a nationwide population-based study

Variables Adults a (n = 6689) Elderly b (n = 6689) Very elderly c (n = 6689) p-value* Post hoc
Treatment duration, days, mean (SD) 277.1 (122.8) 280.6 (123.3) 267.6 (127.2) <0.0001 a,b > c
Treatment persistence rate, n (%)
 at the first 3 months 5753 (86.0) 5764 (86.2) 5663 (84.7) 0.024 b > c
 at the first 6 months 4731 (70.7) 4754 (71.1) 4473 (66.9) <0.0001 a, b > c
 at the first 9 months 4422 (66.1) 4532 (67.8) 4207 (62.9) <0.0001 a, b > c
 at the first 12 months 4179 (62.5) 4364 (65.2) 3979 (59.5) <0.0001 b > a > c
Medication possession ratio, mean (SD) 0.76 (0.30) 0.79 (0.29) 0.75 (0.30) <0.0001 b > a, c
Treatment adherence rate, n (%) 4290 (64.1) 4542 (67.9) 4135 (62.8) <0.0001 b > a > c
  1. *Analysis of variance test or chi-squared test of the three groups
  2. Bonferroni correction (p < 0.015) with student’s t-test or chi-squared test
  3. aAdult cohort bElderly cohort cVery elderly cohort