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Table 2 Outcomes of Monte Carlo simulations

From: The cost-utility of point-of-care troponin testing to diagnose acute coronary syndrome in primary care

Parameter

Without POC troponin (95% CI)

With POC troponin (95% CI)

Absolute effect (POC vs. non-POC) (95% CI)

Relative effect (POC vs. non-POC) (95% CI)

Primary care costs per patient

€290.52

(€188.99 to €421.09)

€262.10

(€173.63 to €375.33)

€-28.41

(€-50.38 to €-12.23)

−9.78%

(−13.36% to −5.75%)

Hospital costs per patient

€446.00

(€307.80 to €620.41)

€398.38

(€277.19 to €551.81)

€-47.62

(€-77.28 to €-25.85)

−10.68%

(−14.27% to −7.12%)

Lifetime costs per patient

€377.55

(€242.56 to €554.17)

€384.13

(€245.85 to €565.96)

€6.58

(€-17.25 to €33.47)

1.74%

(−4.49% to 8.86%)

Costs of productivity loss per patient

€106.87

(€64.71 to €169.27)

€99.07

(€59.52 to €160.09)

€-7.80

(€-18.76 to €2.58)

−7.30%

(−16.94% to 2.70%)

Total costs per patient

€1220.94

(€955.23 to €1540.85)

€1143.68

(€891.74 to €1451.12)

€ -77.25

(€-126.81 to €-33.37)

−6.33%

(−9.80% to −2.85%)

Quality adjusted life expectancy

11.29

(9.41 to 13.33)

11.29

(9.41 to 13.33)

−0.00

(−0.00 to 0.00)

−0.00%

(−0.02% to 0.01%)

Probability TP

3.42%

(2.47% to 4.53%)

3.37%

(2.44% to 4.47%)

−0.05%

(−0.15% to 0.06%)

−1.37%

(−4.08% to 1.64%)

Probability FP

38.46%

(33.97% to 45.00%)

31.85%

(28.29% to 38.70%)

−6.61%

(−8.30% to −4.99%)

−17.19%

(−20.86% to −12.66%)

Probability TN

57.90%

(51.52% to 62.38%)

64.51%

(57.82% to 68.14%)

6.61%

(4.99% to 8.30%)

11.42%

(8.34% to 15.06%)

Probability FN

0.22%

(0.08% to 0.46%)

0.27%

(0.14% to 0.46%)

0.05%

(−0.06% to 0.15%)

20.91%

(−15.72% to 135.02%)

Probability death

0.30%

(0.19% to 0.45%)

0.30%

(0.19% to 0.46%)

0.00%

(−0.01% to 0.03%)

1.53%

(−4.11% to 9.30%)

Probability HF

0.59%

(0.40% to 0.83%)

0.60%

(0.41% to 0.84%)

0.01%

(−0.03% to 0.05%)

1.85%

(−4.24% to 8.91%)

  1. This table shows the results of 10,000 iterations of 20,000 patients, showing the costs and remaining quality-adjusted life expectancy per patient. Both the 95% CI and the absolute and relative effect are provided. CI confidence interval, FN false negative, FP false positive, HF heart failure, POC point-of-care, TN true negative, TP true positive