Parameter | Category | Probability | 95% CI | Distribution | Reference |
---|---|---|---|---|---|
Perceived probability of ACS by GP | High probability | 14.7% | 8.2% to 22.5% | Beta | [15] |
ECG | Performed at GP’s office | 57.4% | 56.0% to 58.7% | Beta | [16] |
Sensitivity for STEMI | 50.0% | 37.6% to 62.6% | Beta | [17] | |
Time from symptom onset to presentation (male) | < 4Â h | 47.5% | 38.9% to 55.4% | Dirichlet | |
4–5.5 h | 9.0% | 5.2% to 14.5% | Dirichlet | ||
5.5–7 h | 7.3% | 3.4% to 11.8% | Dirichlet | ||
7–10 h | 9.4% | 5.2% to 14.9% | Dirichlet | ||
> 10Â h | 26.8% | 20.0% to 34.6% | Dirichlet | ||
Time from symptom onset to presentation (female) | < 4Â h | 54.8% | 47.1% to 62.7% | Dirichlet | |
4–5.5 h | 9.4% | 5.1% to 13.9% | Dirichlet | ||
5.5–7 h | 6.5% | 3.1% to 10.7% | Dirichlet | ||
7–10 h | 8.0% | 4.6% to 13.1% | Dirichlet | ||
> 10Â h | 21.2% | 15.2% to 27.8% | Dirichlet | ||
Diagnostic performance of GP, without POC troponin | Sensitivity | 88.3% | 79.2% to 95.2% | Beta | [18] |
Specificity | 72.2% | 67.9% to 76.3% | Beta | [18] | |
Sensitivity of POC troponin at different duration of symptoms | 4–5.5 h | 66.7% | 55.5% to 77.0% | Beta | [7] |
5.5–7 h | 79.2% | 69.3% to 87.5% | Beta | [7] | |
7–10 h | 84.7% | 75.3% to 91.9% | Beta | [7] | |
> 10Â h | 87.5% | 78.8% to 94.2% | Beta | [7] | |
Specificity of POC troponin at different duration of symptoms | 4–5.5 h | 95.9% | 94.2% to 97.3% | Beta | [7] |
5.5–7 h | 94.4% | 92.5% to 96.1% | Beta | [7] | |
7–10 h | 93.4% | 91.3% to 95.3% | Beta | [7] | |
> 10Â h | 92.6% | 90.4% to 94.5% | Beta | [7] | |
Revise referral decision after discordant POC troponin | Negative troponin | 80.6% | 73.3% to 87.1% | Beta | [15] |
Positive troponin | 83.3% | 76.3% to 89.3% | Beta | [15] |