Table 4 Frequencies of TFPI polymorphisms in two populations according to diabetes mellitus
From: Association study to evaluate TFPI gene in CAD in Han Chinese
SNP | genotype | Population 1 | Population 2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
diabetes mellitus | Non- diabetes mellitus | diabetes mellitus | Non- diabetes mellitus | ||||||||||
CAD n (%) | Non-CAD n(%) | P | CAD n (%) | Non-CAD n (%) | P | CAD n (%) | Non-CAD n (%) | P | CAD n (%) | Non-CAD n (%) | P | ||
Rs8176528 | GG | 225 | 104 | 0.417 | 583 | 725 | <0.001 | 125 | 30 | 0.726 | 338 | 428 | 0.003 |
199 | 76 | 457 | 618 | 65 | 18 | 315 | 366 | ||||||
(88.4) | (73.1) | (78.4) | (85.2) | (52) | (60.0) | (93.2) | (85.5) | ||||||
AA | 9 | 5 | Â | 31 | 41 | Â | 9 | 2 | Â | 9 | 19 | Â | |
(4.0) | (4.8) | (5.3) | (5.7) | (7.2) | (6.7) | (2.7) | (4.4) | ||||||
GA | 17 | 23 | Â | 95 | 66 | Â | 51 | 10 | Â | 14 | 43 | Â | |
(7.6) | (22.1) | (16.3) | (9.1) | (40.8) | (33.3) | (4.1) | (10.1) | ||||||
Rs10153820 | GG | 225 | 104 | 0.002 | 583 | 725 | 0.063 | 125 | 30 | 0.038 | 338 | 428 | 0.392 |
103 | 67 | 312 | 353 | 86 | 15 | 199 | 271 | ||||||
(45.8) | (64.4) | (53.5) | (48.7) | (68.8) | (50.0) | (58.9) | (63.3) | ||||||
AA | 27 | 13 | Â | 21 | 43 | Â | 19 | 4 | Â | 62 | 75 | Â | |
(12.0) | (12.5) | (3.6) | (5.9) | (15.2) | (13.3) | (18.3) | (17.5) | ||||||
GA | 95 | 24 | Â | 250 | 329 | Â | 20 | 11 | Â | 77 | 82 | Â | |
(42.2) | (23.1) | (42.9) | (45.4) | (16.0) | (36.7) | (22.8) | (19.2) | ||||||
225 | 104 | 583 | 725 | 125 | 30 | 338 | 428 | ||||||
Rs6434222 | TT | 107 | 53 | 0.803 | 326 | 443 | <0.001 | 65 | 17 | 0.675 | 170 | 268 | <0.001 |
(47.6) | (51.0) | (55.9) | (61.1) | (52.0) | (56.7) | (50.3) | (62.6) | ||||||
AA | 21 | 8 | Â | 27 | 91 | Â | 5 | 2 | Â | 6 | 58 | Â | |
(9.3) | (7.7) | (4.6) | (12.6) | (4.0) | (6.6) | (1.8) | (13.6) | ||||||
TA | 97 | 43 | Â | 230 | 191 | Â | 55 | 11 | Â | 162 | 102 | Â | |
(43.1) | (41.3) | (39.5) | (26.3) | (44.0) | (36.7) | (47.9) | (23.8) | ||||||
225 | 104 | 583 | 725 | 125 | 30 | 338 | 428 | ||||||
Rs7586970 | TT | 161 | 76 | 0.926 | 520 | 627 | 0.043 | 67 | 13 | 0.065 | 317 | 378 | 0.027 |
(71.6) | (73.1) | (89.2) | (86.5) | (53.6) | (43.3) | (93.8) | (88.3) | ||||||
CC | 13 | 5 | Â | 23 | 52 | Â | 13 | 8 | Â | 8 | 24 | Â | |
(5.8) | (4.8) | (3.9) | (7.2) | (10.4) | (26.7) | (2.4) | (5.6) | ||||||
TC | 51 | 23 | Â | 40 | 46 | Â | 45 | 9 | Â | 13 | 26 | Â | |
(22.6) | (22.1) | (6.9) | (6.3) | (36.0) | (30.0) | (3.8) | (6.1) | ||||||