Disease characteristics | dSSc (n = 62) | lSSc (n = 20) |
---|---|---|
Female/Male | 55/7 | 17/3 |
Age (years) | 43 ± 2 | 38 ± 4 |
Disease duration (months) | 5 ± 3 | 6 ± 1 |
Current smokers | 5 | 1 |
Hypertension | 8 | 1 |
Diabetes | 3 | 0 |
Hyperlipidemia | 6 | 0 |
Lung involvement | 50 | 0 |
Raynaud phenomenon | 58 | 1 |
Digital ulcers | 45 | 0 |
Pulmonary hypertension | 0 | 0 |
GI involvement | 28 | 0 |
Arthritis | 5 | 0 |
ESR, mm/h (normal 3–18) | 10 ± 2 | 13 ± 5 |
CRP, mg/L (normal 2–8) | 4 ± 2 | 2 ± 3 |
Cardiac troponin T (cTnT), ng/mL (normal 0.01 ± 0.03) | 0.006 ± 0.007 | 0.008 ± 0.007 |
mRSS | 20 ± 6 | - |
Anti-centromere antibodies, n (%) | 0 | 12 |
Anti-topoisomerase 1 antibodies, n (%) | 53 | 0 |
Calcium channel blockers | 57 | 8 |
Methotrexate | 15 | 0 |
Prednizolone | 0 | 0 |
Azathioprine | 3 | 0 |
Cloroquine | 2 | 1 |
NSAID | 18 | 3 |