Table 1 Baseline characteristics of study population according to homocysteine level (N = 7002)
From: Plasma homocysteine levels associated with a corrected QT interval
Variables | Homocysteine in quartiles (mmol/L) | P-value | |||
|---|---|---|---|---|---|
Q1 (≤11.1) | Q2(>11.1 and ≤13.8) | Q3 (>13.8 and ≤18.2) | Q4 (>18.2) | ||
Age (year) | 49 ± 9 | 54 ± 10 | 56 ± 10 | 57 ± 12 | <0.001 |
Male gender | 300 (17.2) | 710 (40.8) | 1044 (58.9) | 1206 (69.4) | <0.001 |
Race of Han | 1625 (92.9) | 1660 (95.3) | 1669 (94.2) | 1618 (93.0) | 0.01 |
Smoking | 389 (22.2) | 589 (33.8) | 751 (42.4) | 908 (52.2) | <0.001 |
Drinking | 217 (12.4) | 365 (21.0) | 498 (28.1) | 525 (30.2) | <0.001 |
Sleep duration (h/d) | 7.6 ± 1.6 | 7.3 ± 1.6 | 7.3 ± 1.7 | 7.5 ± 1.8 | 0.122 |
Diet score | 2.2 ± 1.2 | 2.2 ± 1.2 | 2.2 ± 1.2 | 2.3 ± 1.1 | <0.001 |
Education | <0.001 | ||||
Primary school or below | 759 (43.4) | 855 (49.1) | 921 (52.0) | 892 (51.3) | |
Middle school | 830 (47.5) | 723 (41.5) | 677 (38.2) | 703 (40.4) | |
High school or above | 160 (9.1) | 164 (9.4) | 174 (9.8) | 144 (8.3) | |
Physical activity | <0.001 | ||||
Low | 391 (22.4) | 373 (21.4) | 420 (23.7) | 478 (27.5) | |
Moderate | 1242 (71.0) | 1259 (72.3) | 1222 (69.0) | 1176 (67.6) | |
High | 116 (6.6) | 110 (6.3) | 130 (7.3) | 85 (4.9) | |
Family income (CNY/year) | <0.001 | ||||
≤ 5000 | 222 (12.7) | 284 (16.3) | 342 (19.3) | 395 (22.7) | |
5000–20,000 | 993 (56.8) | 978 (56.1) | 1000 (56.4) | 986 (56.7) | |
> 20,000 | 534 (30.5) | 480 (27.6) | 430 (24.3) | 358 (20.6) | |
BMI(kg/m2) | 25.1 ± 3.9 | 24.7 ± 3.7 | 24.7 ± 3.8 | 24.8 ± 3.7 | 0.014 |
WC (cm) | 82.7 ± 9.5 | 83.4 ± 10.0 | 83.7 ± 9.7 | 84.4 ± 10.1 | <0.001 |
SBP (mmHg) | 138.9 ± 23.4 | 140.4 ± 24.1 | 144.9 ± 24.3 | 148.1 ± 26.1 | <0.001 |
DBP(mmHg) | 80.0 ± 11.0 | 81.0 ± 11.8 | 82.4 ± 11.9 | 83.7 ± 12.5 | <0.001 |
FPG (mmol/L) | 5.9 ± 1.9 | 5.9 ± 1.8 | 5.8 ± 1.4 | 5.8 ± 1.6 | 0.002 |
TC (mmol/L) | 5.0 ± 1.1 | 5.1 ± 1.0 | 5.1 ± 1.0 | 5.1 ± 1.0 | 0.009 |
TG (mmol/L) | 1.6 ± 2.1 | 1.6 ± 1.3 | 1.7 ± 1.4 | 1.7 ± 1.6 | <0.001 |
LDL-C (mmol/L) | 2.8 ± 0.8 | 2.8 ± 0.8 | 2.8 ± 0.7 | 2.9 ± 0.8 | <0.001 |
HDL-C (mmol/L) | 1.5 ± 0.4 | 1.4 ± 0.4 | 1.4 ± 0.4 | 1.4 ± 0.4 | <0.001 |
Serum calcium (mmol/L) | 2.385 ± 0.105 | 2.382 ± 0.102 | 2.38 4 ± 0.106 | 2.396 ± 0.105 | <0.001 |
Serum potassium (mmol/L) | 4.189 ± 0.340 | 4.185 ± 0.327 | 4.185 ± 0.329 | 4.18 1 ± 0.364 | 0.72 |
Serum magnesium (mmol/L) | 0.866 ± 0.073 | 0.879 ± 0.069 | 0.883 ± 0.073 | 0.878 ± 0.070 | <0.001 |
History of heart diseasea | 138 (7.9) | 180 (10.3) | 196 (11.1) | 163 (9.4) | 0.01 |
Medication usedb | 936 (53.5) | 933 (53.6) | 979 (55.2) | 981 (56.4) | 0.243 |