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Table 2 Hazard Ratio and Synergy index between Neuroticism and Depression for CVD, IHD and Stroke

From: Effect of neuroticism on risk of cardiovascular disease in depressed persons - a Swedish population-based cohort study

 

CVDa

 

Hypertensive /Ischemic heart diseasea

 

Strokea

 
 

N = 537

 

N = 325

 

N = 248

 
 

Level of Neuroticismb

Level of Neuroticismb

Level of Neuroticismb

 

Low

High

Low

High

Low

High

 

HR (95%CI)

HR (95%CI)

HR (95%CI)

HR (95%CI)

HR (95%CI)

HR (95%CI)

Depression

      

No

1 (Ref)

1.4 (1.1,1.7)

1 (Ref)

1.7 (1.3,2.2)

1 (Ref)

1.2 (0.8,1.6)

Yes

1.0(0.5,2.0)

2.0 (1.5,2.6)

1.0 (0.4,2.8)

2.1 (1.5,3.0)

1.3 (0.5,3.1)

2.0 (1.3,2.9)

Synergy index (95%CI)

 

1.7(0.4,6.3)

 

1.3(0.3,5.6)

 

1.7 (0.2,12.1)

  1. a adjusted for age and gender
  2. b Low level neuroticism is categorized based on the lower and middle tertile