Table 1 Baseline characteristics, presentation and outcomes in the study population without CAD according to troponin subgroups
Normal hsTnT (n = 300) | Elevated hsTnT (n = 173) | Dynamic hsTnT (n = 49) | p-valuea | |
|---|---|---|---|---|
Age (years) | 67 (59–74) | 77 (69–85) | 75 (68–83) | <0.001 |
Male sex | 149 (50%) | 85 (49%) | 21 (43%) | 0.44 |
Current smoking | 41/266 (15%) | 20/153 (13%) | 5/45 (11%) | 0.65 |
Hypertension | 133 (44%) | 102 (59%) | 26 (53%) | 0.27 |
Hyperlipidemia | 59 (20%) | 42 (24%) | 10 (20%) | 0.85 |
Diabetes | 21 (7%) | 28 (16%) | 8 (16%) | 0.05 |
Prior stroke/TIA | 26 (9%) | 26 (15%) | 10 (20%) | 0.01 |
Prior AF/atrial flutter | 160 (53%) | 88 (51%) | 20 (41%) | 0.12 |
CHA2DS2VASc | ||||
≤1 | 131 (44%) | 29 (17%) | 5 (10%) | <0.001 |
2 | 64 (21%) | 35 (20%) | 10 (20%) | 0.88 |
3 | 45 (15%) | 42 (24%) | 15 (31%) | 0.007 |
4 | 37 (12%) | 46 (27%) | 12 (25%) | 0.02 |
≥5 | 23 (8%) | 21 (12%) | 7 (14%) | 0.16 |
Systolic BP (mmHg) | 140 (125–155) | 135 (120–150) | 140 (124–157) | 1.0 |
Heart rate (beats/min) | 132 (119–146) | 138 (126–155) | 137 (127–151) | 0.02 |
Hemoglobin (g/L) | 148 (138–158) | 135 (123–152) | 141 (133–149) | 0.003 |
Creatinine (μg/L) | 83 (69–95) | 96 (76–121) | 88 (72–101) | 0.16 |
CRP (mg/L) | 2.1 (0.9–5.3) | 6.0 (1.8–27) | 3.1 (1.1–12.5) | 0.14 |
Peak hsTnT (ng/L) | 6 (4–10) | 25 (19–36) | 56 (25–101) | <0.001 |
Chest pain | 67 (22%) | 41 (24%) | 20 (41%) | 0.006 |
ST depression | 48 (16%) | 25 (15%) | 17 (35%) | 0.007 |
Atrial fibrillation | 254 (85%) | 147 (85%) | 43 (88%) | 0.67 |
CVD death | 8 (2.7%) | 28 (16%) | 5 (10%) | 0.02 |
All cause mortality | 14 (4.7%) | 50 (29%) | 12 (25%) | 0.001 |
Primary endpoint | 12 (4%) | 10 (5.8%) | 4 (8.2%) | 0.17 |