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Table 1 Individual details of healthy controls and 73 RHVD patients

From: DNA methylation dysregulations in rheumatic heart valve disease

ITEMS

Healthy controls

NYHA II

NYHA III

P

Male: Female (cases)

4 : 0

8 : 21

19 : 25

N/A

Age (years)

44.3 ± 6.70

45.8 ± 10.0

47.7 ± 9.77

> 0.05

Left atrial dimensions (mm)

N/A

53.7 ± 11.2

58.4 ± 13.2

> 0.05

Mitral Valve involvement (N/%)

N/A

29 (100%)

44 (100%)

N/A

Aortic valve involvement (N/%)

N/A

9 (31.0%)

20 (45.5%)

N/A

Stenosis grade

N/A

2.10 ± 0.72

2.52 ± 0.66

0.015*

  1. Stenosis grade: 1. Mild; 2. Moderate; 3. Severe
  2. * P<0.05