Table 1 Patient characteristics and results of treadmill exercise testing
From: Impaired chronotropic response to physical activities in heart failure patients
All patients (N = 40) | ≥70% APMHR (N = 13) | <70% APMHR (N = 13) | P value | |
|---|---|---|---|---|
Age (years) | 54.4 ± 11.7 | 53.1 ± 10.9 | 52.5 ± 13.8 | 0.905 |
Weight (Kg) | 74.8 ± 17.6 | 78.2 ± 19.3 | 74.4 ± 19.4 | 0.634 |
Male, N (%) | 30 (75) | 13 (92.3) | 7 (53.8) | 0.005 |
NYHA class | 2.2 ± 0.6 | 1.9 ± 0.6 | 2.2 ± 0.4 | 0.166 |
LVEF (%) | 44.6 ± 5.8 | 45.8 ± 5.5 | 42.0 ± 5.2 | 0.090 |
LVESD (mm) | 45.9 ± 7.6 | 45.2 ± 7.1 | 49.9 ± 4.8 | 0.066 |
LVEDD (mm) | 59.4 ± 7.7 | 58.2 ± 7.8 | 62.8 ± 4.5 | 0.084 |
6MHW (m) | 413.8 ± 86.9 | 486.2 ± 62.0 | 416.7 ± 37.1 | 0.003 |
SBP (mmHg) | 125.6 ± 18.1 | 126.6 ± 20.1 | 126.8 ± 17.4 | 0.987 |
DBP (mmHg) | 76.8 ± 9.9 | 79.2 ± 10.0 | 76.2 ± 11.4 | 0.528 |
BNP (pg/mL) | 147.5 ± 225.8 | 114.7 ± 96.8 | 124.0 ± 145.9 | 0.855 |
CAD, N (%) | 15 (37.5) | 4 (33.3) | 5 (35.7) | 0.680 |
Cardiomyopathy, N (%) | 35 (87.5) | 11 (84.6) | 12 (92.3) | 0.539 |
Β-blocker, N (%) | 38 (95.0) | 12 (92.3) | 13 (100.0) | 0.308 |
ACE inhibitor, N (%) | 16 (40.0) | 6 (46.2) | 8 (61.5) | 0.431 |
Diuretics, N (%) | 20 (50.0) | 7 (53.8) | 7 (53.8) | 1.000 |
Digoxin, N (%) | 10 (25.0) | 2 (15.4) | 6 (46.2) | 0.089 |
Patients taking treadmill exercise testing (N = 26) | ||||
Rest HR (bpm) | 78.2 ± 10.9 | 80.1 ± 10.1 | 76.2 ± 11.8 | 0.373 |
Maximum HR (bpm) | 112.0 ± 14.8 | 120.1 ± 8.8 | 103.9 ± 15.4 | 0.003 |
HR reserve (bpm) | 33.9 ± 11.9 | 40.0 ± 10.5 | 27.2 ± 10.2 | 0.006 |
APMHR | 167.6 ± 12.5 | 166.8 ± 11.4 | 168.4 ± 14.0 | 0.775 |
Achieved %APMHR | 67.0 ± 6.8 | 72.0 ± 1.2 | 62.0 ± 6.3 | <0.0001 |
C index-β (%) | 62.7 ± 19.6 | 75.3 ± 12.9 | 46.4 ± 15.3 | <0.0001 |