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Table 1 Patient characteristics and results of treadmill exercise testing

From: Impaired chronotropic response to physical activities in heart failure patients

  All patients (N = 40) ≥70% APMHR (N = 13) <70% APMHR (N = 13) P value
Age (years) 54.4 ± 11.7 53.1 ± 10.9 52.5 ± 13.8 0.905
Weight (Kg) 74.8 ± 17.6 78.2 ± 19.3 74.4 ± 19.4 0.634
Male, N (%) 30 (75) 13 (92.3) 7 (53.8) 0.005
NYHA class 2.2 ± 0.6 1.9 ± 0.6 2.2 ± 0.4 0.166
LVEF (%) 44.6 ± 5.8 45.8 ± 5.5 42.0 ± 5.2 0.090
LVESD (mm) 45.9 ± 7.6 45.2 ± 7.1 49.9 ± 4.8 0.066
LVEDD (mm) 59.4 ± 7.7 58.2 ± 7.8 62.8 ± 4.5 0.084
6MHW (m) 413.8 ± 86.9 486.2 ± 62.0 416.7 ± 37.1 0.003
SBP (mmHg) 125.6 ± 18.1 126.6 ± 20.1 126.8 ± 17.4 0.987
DBP (mmHg) 76.8 ± 9.9 79.2 ± 10.0 76.2 ± 11.4 0.528
BNP (pg/mL) 147.5 ± 225.8 114.7 ± 96.8 124.0 ± 145.9 0.855
CAD, N (%) 15 (37.5) 4 (33.3) 5 (35.7) 0.680
Cardiomyopathy, N (%) 35 (87.5) 11 (84.6) 12 (92.3) 0.539
Β-blocker, N (%) 38 (95.0) 12 (92.3) 13 (100.0) 0.308
ACE inhibitor, N (%) 16 (40.0) 6 (46.2) 8 (61.5) 0.431
Diuretics, N (%) 20 (50.0) 7 (53.8) 7 (53.8) 1.000
Digoxin, N (%) 10 (25.0) 2 (15.4) 6 (46.2) 0.089
Patients taking treadmill exercise testing (N = 26)
Rest HR (bpm) 78.2 ± 10.9 80.1 ± 10.1 76.2 ± 11.8 0.373
Maximum HR (bpm) 112.0 ± 14.8 120.1 ± 8.8 103.9 ± 15.4 0.003
HR reserve (bpm) 33.9 ± 11.9 40.0 ± 10.5 27.2 ± 10.2 0.006
APMHR 167.6 ± 12.5 166.8 ± 11.4 168.4 ± 14.0 0.775
Achieved %APMHR 67.0 ± 6.8 72.0 ± 1.2 62.0 ± 6.3 <0.0001
C index-β (%) 62.7 ± 19.6 75.3 ± 12.9 46.4 ± 15.3 <0.0001