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Table 1 Cross-sectional linear regression in the MDC-CC with IMT at baseline as dependent variable and hs-GH as independent. One crude model adjusted for sex and age and one model in addition adjusted for traditional cardiovascular risk factorsa

From: Fasting levels of growth hormone are associated with carotid intima media thickness but are not affected by fluvastatin treatment

Dependent

Gender

Modela

Betab

95%CI

P

IMTmax Bulb

ALL

Crude

0.060

0.020 to 0.099

0.003

 

(n = 3397)

Adjusted

0.066

0.025 to 0.106

0.002

 

MALE

Crude

0.075

0.025 to 0.125

0.003

 

(n = 1440)

Adjusted

0.074

0.022 to 0.125

0.005

 

FEMALE

Crude

0.029

−0.014 to 0.072

0.18

 

(n = 1957)

Adjusted

0.038

−0.006 to 0.083

0.09

IMTmeanCCA

ALL

Crude

−0.012

−0.046 to 0.021

0.48

 

(n = 4425)

Adjusted

0.017

−0.017 to 0.052

0.32

 

MALE

Crude

0.011

−0.033 to 0.054

0.63

 

(n = 1767)

Adjusted

0.024

−0.020 to 0.068

0.28

 

FEMALE

Crude

−0.027

−0.063 to 0.009

0.15

 

(n = 2658)

Adjusted

0.001

−0.036 to 0.038

0.97

  1. aCrude models adjusted for sex and age. Adjusted models adjusted for: sex, age, systolic blood pressure, antihypertensive medication, diabetes mellitus, current smoking, BMI, LDL-C and HDL-C
  2. bThe β coefficients are expressed as the increment of standardized values of the natural logarithm of IMT per 1 increment of standardized values of the natural logarithm of hs-GH