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Fig. 4 | BMC Cardiovascular Disorders

Fig. 4

From: AT1-receptor response to non-saturating Ang-II concentrations is amplified by calcium channel blockers

Fig. 4

TRPC inhibition up-regulates physiological AT1R signaling. a Representative [Ca2+]i traces from Fura Red loaded HEK cells exposed to 1 nM Ang II (at arrows) followed by 5 min treatment with either vehicle (left) or 10 μM BTP2 (right). b Relative change in response between first and second AngII stimulation for vehicle (open bar) and BTP2 (grey bar). n = 4 - 5 experiments, **: p ≤ 0.01 compared to vehicle

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