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Table 2 Arterial blood gas, hematocrit, and hemodynamic variables before and after ECLS

From: Investigation of the pathophysiology of cardiopulmonary bypass using rodent extracorporeal life support model

  Baseline 30 min 60 min 90 min 120 min
pHa
 NC + ECLS 7.54±0.01 7.44±0.01 7.38±0.01 7.40±0.01 7.42±0.01
 CA + ECLS 7.55±0.01 7.43±0.02 7.33±0.02 7.33±0.02 7.32±0.02*
PaO2 (mmHg)
 NC + ECLS 92±2 120±3 99±1 89±1 83±1
 CA + ECLS 90±1 114±3 102±3 87±4 84±4
PaCO2 (mmHg)
 NC + ECLS 28.3±0.6 18.5±0.3 21.8±0.4 23.6±0.4 24.5±0.5
 CA + ECLS 25.9±0.7 19.0±0.8 21.9±1.3 28.6±1.8 27.5±1.9
Base excess (mmol L-1)
 NC + ECLS 1.5±0.2 −11.4±0.3 −12.3±0.3 −10.4±0.3 −8.5±0.3
 CA + ECLS 0±0.2 −11.5±0.7 −13.8±1.2 −10.1±1.3 -10.7±1.5
Hematocrit (%)
 NC + ECLS 40±0 19±0 21±0 23±0 24±0
 CA + ECLS 40±0 17±0 21±0 23±1 25±0
Heart rate (beats min−1)
 NC + ECLS 381.8±3.7 348.5±3.8 398.6±2.7 413.4±2.4 429.6±2.2
 CA + ECLS 384.9±4.4 367.1±5.1 417.2±3.7 430.6±4.8 419.3±8.9
Mean arterial pressure (mmHg)
 NC + ECLS 121.1±0.9 41.0±0.8 58.9±1.2 72.8±1.2 75.1±1.0
 CA + ECLS 113.3±1.3 35.5±1.9 55.6±2.5 73.1±3.0 76.4±3.3
  1. Variables are presented as mean ± SEM. The data depended on the number of surviving rats at each time point. CA + ECLS: asphyxial cardiac arrest rats rescued by ECLS; ECLS: extracorporeal life support; NC + ECLS: normal rats treated with ECLS.
  2. *: P < 0.05 when the CA + ECLS group was compared with the NC + ECLS group at the same time point