Table 1 Baseline characteristics of newly diagnosed heart failure patients stratified by fatigue status at baseline
From: The clinical epidemiology of fatigue in newly diagnosed heart failure
All patients (n = 12,285) | No Fatigue (n = 7458) | Fatigue (n = 4827) | p-value | |
|---|---|---|---|---|
Demographics | ||||
Age, years | 76 (66, 83) | 75 (65, 82) | 77 (67, 84) | <0.001 |
Female, % | 51 | 47 | 57 | <0.001 |
Smoking history, % | 56 | 56 | 54 | 0.030 |
Physical examination | ||||
Body mass index, kg/m2 | 30 (26, 35) | 30 (26, 36) | 29 (25, 35) | <0.001 |
Systolic BP, mm Hg | 128 (117, 142) | 130 (118, 144) | 128 (116, 142) | 0.005 |
Diastolic BP, mm Hg | 70 (62, 80) | 70 (62, 80) | 70 (60, 78) | <0.001 |
Heart rate, bpm | 75 (66, 84) | 74 (64, 84) | 76 (66, 84) | 0.042 |
Medical history | ||||
Abnormal weight loss, % | 11 | 8 | 15 | <0.001 |
Anemia, % | 48 | 41 | 59 | <0.001 |
Anxiety disorder, % | 11 | 9 | 15 | <0.001 |
Aortic aneurysm, % | 7 | 6 | 8 | <0.001 |
Atrial fibrillation, % | 37 | 35 | 40 | <0.001 |
Cancer, % | 30 | 27 | 33 | <0.001 |
Cardiomyopathy, % | 14 | 14 | 14 | 0.272 |
Cerebrovascular disease, % | 34 | 29 | 42 | <0.001 |
Chest pain, % | 53 | 47 | 63 | <0.001 |
Chronic lung disease, % | 39 | 36 | 43 | <0.001 |
Conduction disorder, % | 16 | 14 | 19 | <0.001 |
Coronary atherosclerosis, % | 60 | 59 | 61 | 0.012 |
Dementia, % | 6 | 5 | 8 | <0.001 |
Depression, % | 26 | 19 | 36 | <0.001 |
Diabetes, % | 44 | 44 | 44 | 0.616 |
Dyspnea, % | 62 | 55 | 71 | <0.001 |
Edema, % | 43 | 39 | 50 | <0.001 |
Gastroesophageal reflux, % | 43 | 37 | 53 | <0.001 |
Gout, % | 12 | 12 | 13 | 0.006 |
Hypercholesterolemia, % | 76 | 74 | 80 | <0.001 |
Hyperpotassemia, % | 8 | 7 | 11 | <0.001 |
Hypertension, % | 88 | 86 | 90 | <0.001 |
Hyperthyroidism, % | 3 | 2 | 3 | 0.003 |
Hypopotassemia, % | 17 | 13 | 22 | <0.001 |
Hypothyroidism, % | 26 | 22 | 31 | <0.001 |
Kidney disease, % | 31 | 28 | 36 | <0.001 |
Liver disease, % | 4 | 3 | 5 | <0.001 |
Myocardial infarction, % | 25 | 24 | 26 | <0.001 |
Palpitations, % | 11 | 9 | 15 | <0.001 |
Peripheral vascular disease, % | 27 | 23 | 33 | <0.001 |
Pulmonary embolism, % | 5 | 5 | 7 | <0.001 |
Pulmonary hypertension, % | 14 | 13 | 16 | <0.001 |
Sleep apnea, % | 15 | 13 | 17 | <0.001 |
Syncope, % | 31 | 23 | 43 | <0.001 |
Tachycardia, % | 9 | 8 | 12 | <0.001 |
Valve disease, % | 39 | 36 | 43 | <0.001 |
Venous thromboembolism, % | 7 | 6 | 9 | <0.001 |
Vitamin D deficiency, % | 12 | 8 | 18 | <0.001 |
Volume depletion, % | 11 | 7 | 17 | <0.001 |