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Table 1 Clinical and metabolic characteristics

From: Advanced glycation end products in children with type 1 diabetes and early reduced diastolic heart function

 

E’A’ < 2.0

E’A’ > 2.0

p - value

n = 36

n = 110

Age, years

14.5 (2.2)

13.3 (2.9)

0.008

Girls, n (%)

21 (58.3)

50 (45.5)

0.249

Diabetes duration, yearsa

5.3 (3.5, 6.2)

5.1 (2.5, 8.0)

0.701

Body Mass Index, kg/m2

22.8 (4.0)

20.1 (3.4)

<0 .001

Systolic blood pressure, mmHg

104.2 (8.7)

99.7 (9.3)

0.010

Diastolic blood pressure, mmHg

63.6 (8.3)

59.9 (7.9)

0.016

CRP mg/la

0.59 (0.26, 2.08)

0.40 (0.27, 1.27)

0.348

Actual HbA1c, %

8.3 (1.0)

8.4 (1.4)

0.516

Mean HbA1c, %

7.9 (0.8)

8.1 (1.0)

0.194

Glycemic burden, A1 months

103 (96)

122 (104)

0.354

MG-H1, U/ml

163.9 (39.2)

150.3 (33.4)

0.046

E/E’

8.6 (2.0)

7.9 (1.5)

0.017

cIMT, mm

0.45 (0.05)

0.45 (0.05)

0.901

DC, kPa−1

0.035 (0.010)

0.042 (0.015)

0.013

Young’s modulus, kPa

429 (116)

365 (143)

0.009

Urine albumin/creatinine, mg/mmola

0.6 (0.2, 1.2)

0.8 (0.4, 1.4)

0.248

  1. Mean values (SD)
  2. aMedian (25th and 75th percentile)