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Table 3 Patients characteristics of 7 included studies

From: Thiazolidinedione use and atrial fibrillation in diabetic patients: a meta-analysis

Study, year

Design

Age (years)

T/C

Male

T/C

HF

T/C

HTN

T/C

CAD

T/C

HbA1c (%) T/C

β-blocker

T/C

CCB

T/C

ACEI/ARB

T/C

Statin

T/C

Insulin

T/C

PROactive, 2005 [12]

RCT

61.9/61.6

67%/66%

NA

75%/76%

48%/48%

7.8/7.9

55%/54%

34%/37%

70%/70%

43%/43%

33.2%/34%

Anglade, 2007 [13]

Nested case control study of patients from the AFIST I, II and III trials

65.8/67.2

72.5%/71.5%

15.0%/18.8%

90.0%/75.7%

NA

NA

75.0%/75.0%

12.5%/21.5%

75.0%/56.9%

77.5%/61.8%

NA

RECORD, 2009 [14]

RCT

58.4/58.5

51.4%/51.7%

0.5%/0.4%

NA

NA

7.9/7.9

22.6%/20.9%

19.1%/21.6%

43.1%/42.1%

18%/19.2%

NA

Gu, 2011

Prospective cohort study

59.6/58.7

52.9%/45.5%

0/0

62.7%/72.7%

5.9%/5.1%

6.2/6.4

35.3%/37.4%

35.3%/28.3%

56.9%/45.5%

13.7%/12.1%

3.9%/2.0%

Chao, 2012 [16]

Nested case control study of patients from NHIRD

53.7/54.1

52.9%/53.6%

4.1%/4.7%

38.1%/44.5%

16.9%/18.4%

NA

45.5%/46.4%

NA

68.6%/68.3%

59%/57.4%

0/0

Liu, 2014 [17]

RCT

60.70/62.25

74.3%/ 65.8%

0/0

28.6%/30.3%

28.6%/30.3%

6.41/6.19

41.4%/38.2%

20%/17.1%

NA

31.4%/34.2%

NA

Pallisgaard, 2016 [18]

Prospective cohort study

59.59/62.40

56.7%/ 58.1%

2.3%/4.9%

50.2%/48.4%

NA

NA

31.5%/31.5%

NA

58.8%/55.9%

58.0%/53.0%

NA

  1. Abbreviations: RCT randomized controlled trial, HF heart failure, HTN hypertension, CAD Coronary arterial disease, HbA1c haemoglobin A1c, CCB calcium channel blocker, ACEI angiotensin converting enzyme inhibitor, ARB angiotensin receptor blocker, T/C thiazolidinediones group/control group, NA not applicable