Table 1 Reported outcomes

Connolly 2013 [22]

Stroke or systemic embolism, ischemic stroke, hemorrhagic stroke, MI, pulmonary embolism, major bleeding, life-threatening bleeding, GI bleeding, intracranial bleeding, extracranial bleeding, fatal bleeding, minor bleeding, total mortality

2.3 years

Eikelboon 2013 [23]

Major bleeding, intracranial bleeding, intracerebral bleeding, extracranial bleeding, GI bleeding, life-threatening bleeding, fatal bleeding, minor bleeding

2 years

Larsen 2013 [24]

Stroke, systemic embolism, intracranial bleeding, total mortality, GI bleeding, major bleeding, MI, pulmonary embolism

≥1 year

Maura 2015 [25]

Bleeding events, ischemic stroke or systemic embolism

3 months

Nishtala 2016 [26]

Intracerebral bleeding, GI bleeding

30 days