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Table 1 Patient characteristics by baseline KCCQ score quartile

From: Association of global and disease-specific health status with outcomes following continuous-flow left ventricular assist device implantation

 

Overall

KCCQ Q1

KCCQ Q2

KCCQ Q3

KCCQ Q4

N

3836

552

558

556

559

KCCQ score median (IQR)

34.6 (21.4, 50.5)*

14.3 (9.6, 18.2)

28.1 (25.3, 31.5)

41.1 (37.5, 45.6)

63.8 (56.3, 74.5)

Age in yearsa

 19-20

150 (4)

12 (2)

13 (2)

16 (3)

20 (4)

 30-39

242 (6)

34 (6)

36 (7)

36 (7)

28 (5)

 40-49

513 (13)

90 (16)

70 (13)

65 (12)

68 (12)

 50-59

972 (25)

141 (26)

131 (24)

145 (26)

126 (23)

 60-69

1330 (35)

189 (34)

207 (37)

177 (32)

212 (38)

 70-79

597 (16)

80 (15)

97 (17)

111 (20)

101 (18)

 ≥80

32 (0.8)

6 (1)

4 (0.7)

6 (1)

4 (0.7)

Femaleb

807 (21)

148 (27)

133 (24)

97 (17)

82 (15)

INTERMACS profileb,§

 1 (Critical cardiogenic shock)

500 (13)

66 (12)

27 (5)

23 (4)

26 (5)

 2 (Progressive decline)

1361 (36)

237 (43)

197 (34)

188 (34)

195 (35)

 3 (Stable but inotrope dependent)

1193 (31)

162 (29)

201 (36)

202 (36)

213 (38)

 4 (Resting symptoms)

608 (16)

73 (12)

117 (21)

110 (20)

101 (18)

 5 (Exertion intolerant)

112 (3)

7 (1)

14 (3)

25 (5)

13 (2)

 6 (Exertion limited)

33 (0.9)

2 (0.4)

3 (0.5)

5 (0.9)

5 (0.9)

 7 (Advanced NYHA III)

29 (0.8)

5 (0.9)

5 (0.9)

3 (0.5)

6 (1)

Device strategya

 Bridge to transplant

788 (21)

97 (18)

112 (20)

102 (18)

141 (25)

 Possible bridge to transplant

1326 (35)

169 (31)

178 (32)

183 (33)

167 (30)

 Destination therapy

1,694 (44)

282 (51)

266 (48)

269 (48)

248 (4)

 Other

28 (0.7)

4 (0.7)

2 (0.4)

2 (0.4)

3 (0.6)

Dialysis within 48 h of implantc

40 (1)

9 (2)

1 (0.2)

1 (0.2)

2 (0.4)

Hemoglobin g/L

(g/dL) b

114 ± 21

(11.4 ± 2.1)

112 ± 21

(11.2 ± 2.1)

116 ± 20

(11.6 ± 2.0)

118 ± 20

(11.8 ± 2.0)

118 ± 20

(11.8 ± 2.0)

Sodium mmol/Lb

135 ± 5

134 ± 5

135 ± 5

135 ± 4

136 ± 4

Albumin g/L

(g/dL) b

34 ± 7

(3.4 ± 0.7)

34 ± 06

(3.4 ± 0.6)

35 ± 7

(3.5 ± 0.7)

35 ± 6

(3.5 ± 0.6)

36 ± 6

(3.6 ± 0.6)

IABP¶

918 (24)

146 (26)

89 (16)

86 (16)

71 (13)

Severe depressiond

98 (3)

23 (4)

21 (4)

12 (2)

7 (1)

Working for incomeb

572 (15)

49 (9)

72 (13)

71 (13)

109 (20)

6MWT† feetb

802 ± 412

607 ± 517

746 ± 374

843 ± 367

908 ± 366

Gait speed m/se

0.9 ± 0.8

0.6 ± 0.4

0.9 ± 1.1

0.9 ± 0.4

1.0 ± 1.0

VO2 max mL/kg/mina

11.1 ± 3.7

10.6 ± 5.2

10.6 ± 2.4

11.4 ± 4.4

11.1 ± 2.7

  1. All data are presented as N (%) or mean ± SD unless otherwise specified. All percents are rounded to the nearest whole number
  2. * N = 2225
  3. † 6 min Walk Test
  4. ¶ Intra-aortic balloon pump
  5. § Interagency Registry for Mechanically Assisted Circulatory Support
  6. a p = NS; b p < 0.001 c p = 0.005; d p = 0.010 e p = 0.008