Variable | Control (n = 162) | Mild (n = 213) | Moderate (n = 90) | Severe (n = 78) | P value |
---|---|---|---|---|---|
Age(years) | 55.41 ± 9.28 | 61.35 ± 9.20 | 62.78 ± 9.08 | 66.76 ± 9.85 | < 0.01 |
Male, n (%) | 57(35%) | 109(51%) | 56(62%) | 46(59%) | < 0.01 |
Family history, n(%) | 20(12%) | 26(12%) | 14(16%) | 15(19%) | 0.41 |
Smoking, n (%) | 46(28%) | 93(44%) | 50(56%) | 43(55%) | < 0.01 |
DM, n (%) | 25(15%) | 60(28%) | 45(50%) | 34(44%) | < 0.01 |
HT, n (%) | 85(52%) | 157(74%) | 67(74%) | 67(86%) | < 0.01 |
HGB (g/L) | 135.33 ± 15.87 | 136.52 ± 14.30 | 138.84 ± 17.09 | 133.88 ± 16.63 | 0.18 |
Platelet (109/L) | 221.32 ± 51.31 | 215.01 ± 53.60 | 206.66 ± 57.82 | 205.73 ± 46.94 | 0.08 |
Leukocyte (109/L) | 6.07(4.99–7.13) | 6.41(5.36–7.50) | 6.92(6.00–8.18) | 6.67(5.80–8.08) | < 0.01 |
Neutrophil (109/L) | 3.42(2.95–4.41) | 3.90(3.20–4.63) | 4.73(3.81–5.49) | 4.67(3.80–5.70) | < 0.01 |
Monocyte (108/L) | 3.02(2.51–3.62) | 3.52(3.04–4.38) | 4.24(3.36–4.92) | 4.81(3.56–5.62) | < 0.01 |
Lymphocyte (109/L) | 1.95(1.49–2.29) | 1.84(1.46–2.28) | 1.70(1.37–2.06) | 1.37(1.10–1.91) | < 0.01 |
FBG (mmol/L) | 5.35(4.93–5.88) | 6.04(5.27–7.24) | 6.74(5.53–9.41) | 6.34(5.56–8.15) | < 0.01 |
TC (mmol/L) | 4.84 ± 1.10 | 5.03 ± 1.10 | 4.88 ± 1.19 | 5.04 ± 1.13 | 0.35 |
TG (mmol/L) | 1.51(1.06–2.23) | 1.57(1.17–2.30) | 1.47(1.12–2.31) | 1.42(1.04–2.19) | 0.34 |
LDL (mmol/L) | 2.65(2.12–3.25) | 2.76(2.23–3.35) | 2.57(2.09–3.44) | 2.88(2.29–3.48) | 0.40 |
HDL (mmol/L) | 1.16(0.94–1.39) | 1.09(0.92–1.29) | 1.04(0.92–1.27) | 1.15(0.90–1.31) | 0.12 |
SCr (μmol/L) | 71.34(59.27–83.51) | 73.36(62.94–86.25) | 79.35(65.35–92.30) | 81.64(65.85–92.96) | < 0.01 |
UA (μmol/L) | 334.12 ± 93.41 | 331.93 ± 88.51 | 335.62 ± 88.79 | 345.44 ± 102.95 | 0.74 |
NLR | 1.87(1.42–2.36) | 2.09(1.64–2.77) | 2.73(2.24–3.34) | 3.37(2.50–4.75) | < 0.01 |
MLR | 0.16(0.13–0.21) | 0.20(0.15–0.25) | 0.23(0.19–0.31) | 0.29(0.21–0.43) | < 0.01 |