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Table 2 Baseline clinical and angiographic features based on quartiles of B2M

From: High levels of serum β2-microglobulin predict severity of coronary artery disease

Characteristics

Quartile 1

Quartile 2

Quartile 3

Quartile 4

p-value

≤1.00 (mg/L) n = 472

1.00–1.17(mg/L) n = 443

1.18–1.35(mg/L) n = 431

>1.35(mg/L) n = 416

Baseline clinical features

 Age (years)

53.85 ± 9.44

56.49 ± 9.12

60.38 ± 8.53

61.58 ± 9.55

<0.001

 Gender (male, %)

63.0

68.7

65.8

63.9

0.285

 Smoker (%)

33.3

38.3

34.9

32.0

0.242

 Drinker (%)

25.5

28.0

21.7

18.3

0.005

 Hypertension (%)

52.9

59.0

61.3

67.7

<0.001

 Diabetes (%)

15.2

16.0

15.5

22.1

0.022

 AMI (%)

3.6

5.9

8.5

6.9

0.018

 HF (%)

0.4

0.5

0.9

0.7

0.751

Baseline blood features

 TG (mmol/L)

1.86 ± 1.33

2.01 ± 5.09

2.12 ± 7.51

1.64 ± 1.03

0.228

 TC (mmol/L)

4.39 ± 0.99

4.42 ± 1.01

4.39 ± 1.88

5.26 ± 20.39

0.044

 HDL-C (mmol/L)

1.14 ± 0.49

1.38 ± 4.98

1.1 ± 0.33

1.09 ± 0.58

0.000

 LDL-C (mmol/L)

2.65 ± 0.82

2.74 ± 0.92

2.62 ± 0.85

3.49 ± 17.6

0.295

 Apo-A (g/L)

1.31 ± 0.29

1.41 ± 1.15

1.27 ± 0.26

1.25 ± 0.38

<0.001

 Apo-B (g/L)

1.25 ± 6.59

1.19 ± 5.19

0.94 ± 0.4

0.94 ± 0.36

0.730

 Creatinine (umol/L)

64.13 ± 13.68

68.48 ± 13.12

71.36 ± 15.56

77.4 ± 16.13

<0.001

 BUN (mmol/L)

5.78 ± 14.45

5.15 ± 1.26

6.89 ± 19.98

6.74 ± 23.13

<0.001

 UA (umol/L)

272.97 ± 76.96

299.38 ± 88.34

300.06 ± 120.89

338.75 ± 301.73

<0.001

Angiographic features

 CAD (%)

68.1

75.7

79.1

86.1

<0.001

 Severe CADa (%)

29.4

46.5

52.2

82.2

<0.001

 Number of stenotic arteries

   

<0.001

  0 (%)

37.2

27.1

22.3

21.7

 

  1 (%)

26.6

28.0

25.6

21.3

 

  2 (%)

22.1

25.2

26.2

24.5

 

  3 (%)

14.1

19.8

25.9

32.6

 

Gensini score

24.94 ± 31.95

28.31 ± 34.42

30.02 ± 32.54

39.5 ± 37.73

<0.001

  1. aSevere CAD defined as the patients with number of stenotic arteries ≥2. Data are means ± SD
  2. CAD coronary artery disease, AMI acute myocardial infarction, HF heart failure, SBP systolic blood pressure, DBP, diastolic blood pressure, HR heart rate, BUN blood urea nitrogen, UA uric acid, TG Triglycerides, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, Apo-A Apolipoprotein A, Apo-B Apolipoprotein B, B2M β2-microglobulin