From: High levels of serum β2-microglobulin predict severity of coronary artery disease
Characteristics | Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | p-value |
---|---|---|---|---|---|
≤1.00 (mg/L) n = 472 | 1.00–1.17(mg/L) n = 443 | 1.18–1.35(mg/L) n = 431 | >1.35(mg/L) n = 416 | ||
Baseline clinical features | |||||
Age (years) | 53.85 ± 9.44 | 56.49 ± 9.12 | 60.38 ± 8.53 | 61.58 ± 9.55 | <0.001 |
Gender (male, %) | 63.0 | 68.7 | 65.8 | 63.9 | 0.285 |
Smoker (%) | 33.3 | 38.3 | 34.9 | 32.0 | 0.242 |
Drinker (%) | 25.5 | 28.0 | 21.7 | 18.3 | 0.005 |
Hypertension (%) | 52.9 | 59.0 | 61.3 | 67.7 | <0.001 |
Diabetes (%) | 15.2 | 16.0 | 15.5 | 22.1 | 0.022 |
AMI (%) | 3.6 | 5.9 | 8.5 | 6.9 | 0.018 |
HF (%) | 0.4 | 0.5 | 0.9 | 0.7 | 0.751 |
Baseline blood features | |||||
TG (mmol/L) | 1.86 ± 1.33 | 2.01 ± 5.09 | 2.12 ± 7.51 | 1.64 ± 1.03 | 0.228 |
TC (mmol/L) | 4.39 ± 0.99 | 4.42 ± 1.01 | 4.39 ± 1.88 | 5.26 ± 20.39 | 0.044 |
HDL-C (mmol/L) | 1.14 ± 0.49 | 1.38 ± 4.98 | 1.1 ± 0.33 | 1.09 ± 0.58 | 0.000 |
LDL-C (mmol/L) | 2.65 ± 0.82 | 2.74 ± 0.92 | 2.62 ± 0.85 | 3.49 ± 17.6 | 0.295 |
Apo-A (g/L) | 1.31 ± 0.29 | 1.41 ± 1.15 | 1.27 ± 0.26 | 1.25 ± 0.38 | <0.001 |
Apo-B (g/L) | 1.25 ± 6.59 | 1.19 ± 5.19 | 0.94 ± 0.4 | 0.94 ± 0.36 | 0.730 |
Creatinine (umol/L) | 64.13 ± 13.68 | 68.48 ± 13.12 | 71.36 ± 15.56 | 77.4 ± 16.13 | <0.001 |
BUN (mmol/L) | 5.78 ± 14.45 | 5.15 ± 1.26 | 6.89 ± 19.98 | 6.74 ± 23.13 | <0.001 |
UA (umol/L) | 272.97 ± 76.96 | 299.38 ± 88.34 | 300.06 ± 120.89 | 338.75 ± 301.73 | <0.001 |
Angiographic features | |||||
CAD (%) | 68.1 | 75.7 | 79.1 | 86.1 | <0.001 |
Severe CADa (%) | 29.4 | 46.5 | 52.2 | 82.2 | <0.001 |
Number of stenotic arteries | <0.001 | ||||
0 (%) | 37.2 | 27.1 | 22.3 | 21.7 | |
1 (%) | 26.6 | 28.0 | 25.6 | 21.3 | |
2 (%) | 22.1 | 25.2 | 26.2 | 24.5 | |
3 (%) | 14.1 | 19.8 | 25.9 | 32.6 | |
Gensini score | 24.94 ± 31.95 | 28.31 ± 34.42 | 30.02 ± 32.54 | 39.5 ± 37.73 | <0.001 |