Table 3 Gene-smoking and gene-diabetes interaction in patients with CAD cases and controls
Variables | CAD cases | Controls | OR (95% CI) | P | adjusted OR a (95% CI) | P | |
|---|---|---|---|---|---|---|---|
rs36071027 | Smoking | ||||||
CC | No | 132 (45.1) | 160 (61.1) | 1 | 1 | ||
CC | Yes | 79 (27.0) | 51 (19.5) | 1.88 (1.23–2.86) | 0.003 | 1.89 (1.15–3.12) | 0.012 |
CT + TT | No | 54 (18.4) | 38 (14.5) | 1.72 (1.07–2.77) | 0.025 | 1.80 (1.11–2.93) | 0.017 |
CT + TT | Yes | 28 (9.6) | 13 (5.0) | 2.61 (1.30–5.24) | 0.007 | 2.55 (1.22–5.30) | 0.013 |
P interation | 0.882 | 0.747 | |||||
rs36071027 | Diabetes | ||||||
CC | No | 147 (50.2) | 165 (63.0) | 1 | 1 | ||
CC | Yes | 64 (21.8) | 46 (17.6) | 1.56 (1.01–2.42) | 0.047 | 1.58 (1.00–2.49) | 0.050 |
CT + TT | No | 54 (18.4) | 43 (16.4) | 1.41 (0.89–2.23) | 0.142 | 1.40 (0.88–2.23) | 0.160 |
CT + TT | Yes | 28 (9.6) | 8 (3.1) | 3.93 (1.74–8.89) | 0.001 | 3.84 (1.68–8.78) | 0.001 |
P interation | 0.249 | 0.280 |