Association in a Chinese population of a genetic variation in the early B-cell factor 1 gene with coronary artery disease

Table 2 Association analyses of rs36071027 genotypes in the EBF1 gene between CAD patients and controls

Genotypes	CAD cases (n = 293)	Controls (n = 262)	OR (95% CI)	P	Multiple adjusted OR^a (95% CI)	P
Genotypes	n (%)	n (%)	OR (95% CI)	P	Multiple adjusted OR^a (95% CI)	P
rs36071027
CC	211 (72.0)	211 (80.5)	1		1
CT	68 (23.2)	47 (17.9)	1.45 (0.953–2.20)	0.083	1.48 (0.96–2.27)	0.074
TT	14 (4.8)	4 (1.5)	3.50 (1.13–10.81)	0.029	2.98 (0.94–9.46)	0.064
Additive model			1.59 (1.13–2.23)	0.008	1.56 (1.10–2.22)	0.013
Dominant model			1.61 (1.08–2.39)	0.019	1.60 (1.07–2.41)	0.023

Abbreviations: OR, odds ratio; CI, confidence interval
^aLogistic regression model, adjusted by age, sex, hypertension, diabetes, smoking, body mass index and hyperlipidemia
Additive model: TT vs. CC. Dominant model: (TT + CT) vs. CC

ISSN: 1471-2261