Variables | Group 1 | Group 2 | p-value (1 vs 2) | Group 3 | Group 4 | p-value (3 vs 4) | p-value (1/2 vs 3/4) |
---|---|---|---|---|---|---|---|
Age (year) | 58.9 ± 10.04 | 59 ± 10.89 | 0.896 | 63.88 ± 8.32 | 61.41 ± 10.04 | 0.020 | <0.001 |
Male (%) | 182 (55.83%) | 259 (56.67%) | 0.814 | 84 (70%) | 148 (77.89%) | 0.119 | <0.001 |
Symptoms | |||||||
Asymptomatic | 70 (20.5%) | 66 (14.4%) | 0.001 | 75 (62.5%) | 96 (50.5%) | 0.078 | <0.001 |
Atypical chest pain | 127 (39.0%) | 149 (32.6%) | 15 (12.5%) | 24 (12.6%) | |||
Typical chest pain | 129 (39.6%) | 242 (53.0%) | 30 (25.0%) | 70 (36.8%) | |||
BMI (kg/m2) | 24.9 ± 3.09 | 24.71 ± 2.97 | 0.391 | 24.68 ± 2.8 | 24.99 ± 3.04 | 0.356 | 0.683 |
Smoking (%) | 97 (29.75%) | 138 (30.2%) | 0.894 | 38 (31.67%) | 51 (26.84%) | 0.360 | 0.671 |
Hypertension (%) | 191 (58.4%) | 266 (58.3%) | 1.000 | 108 (90.0%) | 180 (94.7%) | 0.172 | <0.001 |
Diabetes mellitus (%) | 61 (18.71%) | 82 (17.94%) | 0.784 | 46 (38.33%) | 50 (26.32%) | 0.026 | <0.001 |
Dyslipidemia (%) | 95 (29.14%) | 149 (32.6%) | 0.302 | 102 (85%) | 164 (86.32%) | 0.746 | <0.001 |
CKD (%) | 69 (21.23%) | 110 (24.07%) | 0.352 | 42 (35%) | 53 (27.89%) | 0.186 | 0.008 |
Uric acid (mg/dL) | 5.14 ± 1.48 | 5.25 ± 1.44 | 0.337 | 5.3 ± 1.63 | 5.42 ± 1.34 | 0.493 | 0.085 |
Hba1c (% of THb) | 6.19 ± 1.04 | 6.29 ± 1.41 | 0.539 | 6.48 ± 1.08 | 6.02 ± 0.82 | 0.005 | 0.644 |
TC (mg/dL) | 147.8 ± 89.48 | 157.3 ± 103.2 | 0.168 | 123.7 ± 63.19 | 133.7 ± 80.2 | 0.226 | <0.001 |
LDL-C (mg/dL) | 96.5 ± 26.88 | 96.13 ± 27.24 | 0.853 | 72.64 ± 20.31 | 73.07 ± 21.8 | 0.860 | <0.001 |
HDL-C (mg/dL) | 51.31 ± 13.57 | 49.95 ± 12.83 | 0.157 | 48.1 ± 11.29 | 46.89 ± 11.36 | 0.361 | <0.001 |
Triglyceride (mg/dL) | 137.5 ± 89.21 | 152.3 ± 105.9 | 0.036 | 119.6 ± 67.36 | 129.9 ± 82.59 | 0.231 | <0.001 |
Creatinine (mg/dL) | 0.96 ± 0.46 | 0.95 ± 0.23 | 0.672 | 1.06 ± 0.65 | 1.02 ± 0.2 | 0.479 | 0.003 |
hsCRP (mg/L) | 2.74 ± 8.99 | 2.15 ± 5.68 | 0.324 | 2.01 ± 4.32 | 1.82 ± 4 | 0.701 | 0.162 |
#, risk factorsa | 2.23 ± 1.39 | 2.29 ± 1.35 | 0.579 | 3.67 ± 1.25 | 3.48 ± 0.97 | 0.152 | <0.001 |
Index Medications | |||||||
ACE inhibitors (%) | 12 (3.68%) | 15 (3.28%) | 0.763 | 35 (29.17%) | 55 (28.95%) | 0.967 | <0.001 |
ARBs (%) | 87 (26.69%) | 101 (22.1%) | 0.139 | 52 (43.33%) | 68 (35.79%) | 0.184 | <0.001 |
Beta-blockers (%) | 35 (10.74%) | 62 (13.57%) | 0.236 | 47 (39.17%) | 88 (46.32%) | 0.216 | <0.001 |
CCB (%) | 84 (25.77%) | 135 (29.54%) | 0.246 | 47 (39.17%) | 83 (43.68%) | 0.432 | <0.001 |
Diuretics (%) | 27 (8.28%) | 28 (6.13%) | 0.245 | 12 (10%) | 15 (7.89%) | 0.522 | 0.340 |
Insulin (%) | 2 (0.61%) | 2 (0.44%) | 1.000 | 4 (3.33%) | 5 (2.63%) | 0.739 | 0.003 |
Statins (%) | 77 (23.62%) | 116 (25.38%) | 0.573 | 102 (85%) | 163 (85.79%) | 0.848 | <0.001 |