Table 2 Markers of inflammation in patients with myocardial infarction with and without visceral obesity, Me (Q1;Q3)
Variable | Control group, n = 30 | Patients with visceral obesity, n = 160 | Patients without visceral obesity, n = 72 | ||
|---|---|---|---|---|---|
1st day | 12st day | 1st day | 12st day | ||
1 | 2 | 3 | 4 | 5 | |
TNF-α, pg/ml | 1.2 (0.9;1.4) | 1.4 (1.0;1.7) p1-2 = 0.01 | 1.9 (1.4;2.0) p1–3 = 0.01 p2–3 = 0.02 | 1.2 (0.7;1.6) p2–4 = 0.002 | 1.0 (0.8;2.1) p3–5 = 0.003 |
IL -1β, pg/ml | 2.2 (2,1;4,3) | 5.2 (2.6;6.2) p1–2 = 0,001 | 4.9 (2.7;6.6) p1–3 = 0.002 | 3.3 (2.0;4.4) p2–4 = 0.003 | 2,4 (1.1;5.4) p3–5 = 0.002 |
IL −6, pg/ml | 2.55 (2,1;3,3) | 17.5 (11.7; 25.1) p1–2 = 0.001 | 9.5 (3.2; 4.3) p1–3 = 0.01 p2–3 = 0.02 | 12.0 (6.9;18.7) p1–4 = 0.006 p2–4 = 0.004 | 6.1 (2.5;14.1) p1–5 = 0.002 p3–5 = 0.001 p4–5 = 0.01 |
IL −8, pg/ml | 2.4 (2.1;4.1) | 58.0 (29.9;69.5) p1–2 = 0.001 | 48,3 (40.4;64.4) p1–3 = 0.00 p2–3 = 0.01 | 45.5 (27.4;54.7) p1–4 = 0.005 p2–4 = 0.004 | 43,6 (35,3;52.2) p1–5 = 0.003 p3–5 = 0.004 |
IL −12, pg/ml | 60.4 (47.2;88.6) | 128.7 (66.4;182.0) p1–2 = 0.001 | 98.4 (86.7;261.2) p1–3 = 0.005 p2–3 = 0.02 | 100.1 (48.0;151.7) p1–4 = 0.007 p2–4 = 0.03 | 55.3 (44.0;101.3) p3–5 = 0.02 p4–5 = 0.01 |
CRP, mg/l | 1.0 (0.8;1.5) | 23.2 (12.1;54.1) p1–2 = 0.008 | 11.3 (5.0;21.6) p1–3 = 0.00 p2–3 = 0.01 | 20.2 (12.8;35.0) p1–4 = 0.003 p2–4 = 0.001 | 7.7 (4.7;15.0) p1–5 = 0.005 p3–5 = 0.004 p4–5 = 0.01 |
IL −10, pg/ml | 8.9 (7.4;10.2) | 1.9 (0.7;2.5) p1–2 = 0.00 | 3.8 (1.1;4.5) p1–3 = 0.00 p2–3 = 0.01 | 5.6 (3.2;6.2) p1–4 = 0.00 p2–4 = 0.02 | 7.8 (6.8;9.7) p1–5 = 0.00 p3–5 = 0.01 p4–5 = 0.01 |