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Table 1 Clinical and biochemical characteristics of CAD patients and controls

From: Atherosclerotic and thrombotic genetic and environmental determinants in Egyptian coronary artery disease patients: a pilot study

Characteristics

Controls (n = 34)

Patients (n = 23)

p value

OR (95% CI)

Age, mean (y)

54.7 ± 10.1

54.0 ± 10.1

0.810

 

Gender

 Females

16 (47.1)

6 (26.1)

0.166

Reference

 Males

18 (52.9)

17 (73.9)

 

2.51 (0.79–7.94)

BMI, kg/m2

27.7 ± 1.86

28.1 ± 2.07

0.435

 

Obesity

6 (17.6)

5 (21.7)

0.742

1.29 (0.34–4.88)

Smoking

--

13 (56.5)

  

FH CAD

12 (35.3)

6 (26.1)

0.567

0.64 (0.20–2.07)

Hypertension

--

10 (43.5)

  

Diabetes

12 (35.3)

7 (30.4)

0.780

0.82 (0.25–2.49)

Dyslipidemia

--

19 (82.6)

  

Biochemical data

 FBS (mg/dl)

99.4 ± 25.7

145.6 ± 62.2

<0.001

 

 TC (mg/dl)

170 ± 18.4

207 ± 61.5

0.001

 

 TG (mg/dl)

103 ± 33.1

155 ± 54.4

<0.001

 

 LDL-c (mg/dl)

74.9 ± 12.6

147 ± 66.3

<0.001

 

 HDL-c (mg/dl)

48.6 ± 8.3

37.8 ± 11.4

<0.001

 

No of risk factors

  ≤ 3

32 (94.1)

9 (39.1)

<0.001

Reference

  > 3

2 (5.9)

14 (60.9)

 

24.8 (4.75–130)

Premature CAD

--

9 (39.1)

  

Previous events

--

18 (78.3)

  

Stroke

--

1 (4.3)

  

Lesion type

 100% Normal

--

5 (21.7)

  

  < 50% Occlusion

--

3 (13.0)

  

 50- 99% Occlusion

--

9 (39.2)

  

 100% Occlusion

--

6 (26.1)

  

Lesion site

 Single VD

--

8 (34.8)

  

 Two VD

--

4 (17.4)

  

 Three VD

--

6 (26.1)

  

CAD severity

 Gensini score

--

14 (1.5–62)

  

 Vessel score

--

1.0 (0.0–3.0)

  

Echo findings

 Ejection fraction

–

57.4 ± 7.98

  

 Mild DD

--

20 (87.0)

  

 SWMA

--

9 (39.1)

  
  1. Values are shown as a number (percentage), mean ± standard deviation, or median (quartiles). CAD coronary artery disease; OR (95% CI), Odds ratio (95% confidence interval); FH family history, FBS fasting blood sugar, TC total cholesterol, TG triglycerides, LDL-c low density lipoprotein-cholesterol, HDL-c high density lipoprotein-cholesterol; Risk factors, Age (men ≥ 45 y and women ≥ 55 y), family history of premature coronary artery disease, hypertension, cigarette smoking, diabetes, hypercholesterolemia, low HDL cholesterol <40 mg/dl, hypertriglyceridemia > 200 mg/dl, and obesity; Premature coronary artery disease, <55 years in males and <65 years in females; previous events, previous acute coronary ischemic events; VD vessel disease (defined as luminal narrowing of > 70%); Gensini score to asses disease severity; DD diastolic dysfunction; SWMA, systolic wall motion abnormalities. P value was generated by using Fisher’s exact test, and Student’s t tests. The bold data are statistically significant at p < 0.05