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Table 2 General features of the studies included

From: Is the concomitant use of clopidogrel and Proton Pump Inhibitors still associated with increased adverse cardiovascular outcomes following coronary angioplasty?: a systematic review and meta-analysis of recently published studies (2012 – 2016)

Studies

No of patients using clopidogrel + PPIs (n)

No of patients using clopidogrel alone (n)

Type of study

Region

Bhurke 2012

2958

7143

Retrospective

United states

Burkard 2012

109

692

Retrospective

United states

Chitose 2012

187

443

Observational

Japan

Douglas 2012

12439

16900

Observational

United Kingdom

Dunn 2013

408

9191

Retrospective

Charlottesville

Goodman 2012

3255

6021

RCT

Canada

Hsieh 2015

670

5933

Observational

Taiwan

Macaione 2012

121

55

Retrospective

Italy

Weisz 2015

2162

6419

Observational

Israel

Zou 2014

6188

1465

Observational

China

Gargiolo 2016

738

1232

RCT

Italy

Total no of patients (n)

29,235

55,494

  
  1. Abbreviations: PPIs Proton pump inhibitor, RCT Randomized controlled trial