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Table 3 Comparison of baseline characteristics of <80% versus ≥80% average adherence to benzathine penicillin

From: Rheumatic heart disease in Uganda: predictors of morbidity and mortality one year after presentation

  Female Male
  <80% ≥80% P-Value <80% ≥80% P-Value
Age
 ≤15 years 31 (8.49) 85 (18.24) <0.001 24 (17.91) 39 (18.57) <0.001
 16–30 year 66 (18.08) 191 (40.99)   52 (38.81) 91 (43.33)  
 31–49 years 159 (43.56) 167 (35.84)   38 (28.36) 77 (36.67)  
 >50 year 109 (29.86) 23 (4.94)   20 (14.93) 3 (1.43)  
Education level
 No education 86 (23.56) 24 (5.15) <0.001 10 (7.46) 7 (3.33) 0.022
 Primary 150 (41.10) 200 (42.92)   61 (45.52) 101 (48.10)  
 Secondary 80 (21.92) 166 (35.62)   54 (40.30) 69 (32.86)  
 Post secondary 49 (13.42) 76 (16.31)   9 (6.72) 33 (15.71)  
NYHA at baseline
 Class 1 191 (52.33) 241 (51.72) 0.823 53 (39.55) 81 (38.57) 0.833
 Class 2 97 (26.58) 121 (25.97)   38 (28.36) 58 (27.62)  
 Class 3 70 (19.18) 98 (21.03)   41 (30.60) 64 (30.48)  
 Class 4 7 (1.92) 6 (1.29)   2 (1.49) 7 (3.33)  
Heart failure
 No 201 (55.07) 312 (66.95) <0.001 56 (42.11) 120 (57.14) 0.007
 Yes 164 (44.93) 154 (33.05)   77 (57.89) 90 (42.86)  
ARF at baseline
 No 341 (93.42) 386 (82.83) <0.001 117 (87.31) 177 (84.29) 0.437
 Yes 24 (6.58) 80 (17.17)   17 (12.69) 33 (15.71)  
Stroke
 No 349 (95.62) 465 (99.79) <0.001 129 (96.27) 210 (100) 0.009
 Yes 16 (4.38) 1 (0.21)   5 (3.73) 0 (0.0)  
Infective endocarditis
 No 352 (96.44) 455 (97.64) 0.305 121 (90.30) 210 (100) <0.001
 Yes 13 (3.56) 11 (2.36)   13 (9.70) 0 (0.0)  
Atrial fibrillation
 No 242 (66.30) 419 (89.91) <0.001 102 (76.12) 176 (83.81) 0.077
 Yes 123 (33.70) 47 (10.09)   32 (23.88) 34 (16.19)  
LVIDd
 <55 mm 208 (56.99) 282 (60.52) 0.305 56 (41.79) 109 (51.90) 0.067
 ≥55 mm 157 (43.01) 184 (39.48)   78 (58.21) 101 (48.10)  
LVIDs
 <40 mm 253 (69.32) 334 (71.67) 0.459 79 (58.96) 152 (72.38) 0.010
 ≥40 mm 112 (30.68) 132 (28.33   55 (41.04) 58 (27.62)  
Ejection fraction
 <40% 92 (25.48) 124 (26.61) 0.715 36 (26.87) 53 (25.24) 0.737
 ≥40% 269 (74.52) 342 (73.39)   98 (73.13) 157 (74.76)  
Left atrial diameter
 <40 mm 79 (21.64) 124 (26.61) 0.098 11 (8.21) 31 (14.76) 0.070
 ≥40 mm 286 (78.36) 342 (73.39)   123 (91.79) 179 (85.24)  
ASO
 <240 339 (94.17) 383 (82.90) <0.001 117 (87.31) 181 (86.19) 0.765
 ≥240 21 (5.83) 79 (17.10)   17 (12.69) 29 (13.81)  
CRP
 <5 mg/L 227 (63.06) 335 (73.63) 0.001 87 (64.93) 129 (61.43) 0.513
 ≥5 mg/L 133 (36.94) 120 (26.37)   47 (35.07) 81 (38.57)  
  1. Values shown are number (%)